The Pool sign in Metastatic Adenocarcinoma of Brain
Bibliographic record
Abstract
CASE DETAILSMajority of intracranial lesions may present as a solitary mass, with two main differentialsa primary intracranial neoplasm and metastasis.These lesions offer a greater diagnostic challenge to both the clinician and radiologist, and often these patients undergo biopsy.Prompt diagnosis is required due to differences in the management and clinical outcomes of primary tumor and metastasis.In case of a metastatic lesion, further workup is necessary to find the primary malignancy.We present the case of a 60-year-old female, with no comorbidities, presented with a history of left-sided weakness and new onset seizures.Her cerebrospinal fluid study was normal, Mantoux, tuberculosis polymerase chain reaction and tumor markers were negative.Her brain magnetic resonance imaging (MRI) showed a ring-enhancing lesion in the right parietal lobe with perilesional edema.Also, there was a perilesional T2 hyperintense rim "the pool sign" immediately adjacent to the solid mass, deep to the peritumoral vasogenic edema.Her computed tomography scan of the chest showed a right lung mass, biopsy of which confirmed an adenocarcinoma (Figure 1)."The pool sign" is typically higher in
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.005 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".