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Record W3096039660 · doi:10.1101/2020.11.04.365999

Challenges in Undergraduate Synthetic Biology Training: Insights from a Canadian iGEM Student Perspective

2020· preprint· en· W3096039660 on OpenAlexaffabout
Patrick Diep, Austin Boucinha, Bi-ru Amy Yeung, Brayden Kell, Xingyu Chen, Daniel Tsyplenkov, Danielle Serra, Andres Escobar, Ansley Gnanapragasam, Christian A. Emond, Victoria A. Sajtovich, Radhakrishnan Mahadevan, Dawn M. Kilkenny, Garfield Gini-Newman, Mads Kærn, Brian Ingalls

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2020
Typepreprint
Languageen
FieldEngineering
TopicBiomedical and Engineering Education
Canadian institutionsUniversity of OttawaConcordia UniversityUniversity of CalgaryMcGill UniversityQueen's UniversityUniversity of WaterlooUniversity of Toronto
Fundersnot available
KeywordsSynthetic biologyPerspective (graphical)Engineering ethicsBiologyComputer scienceEngineeringComputational biologyArtificial intelligence

Abstract

fetched live from OpenAlex

ABSTRACT The last two decades have seen vigorous activity in synthetic biology research and ever-increasing applications of synthetic biology technologies. However, pedagogical research on synthetic biology is scarce, especially when compared to some scientific and engineering disciplines. Within Canada, there are only three universities that formally teach synthetic biology programs; two of which are at the undergraduate level. Many Canadian undergraduate students are instead introduced to synthetic biology through participation in the annual International Genetically Engineered Machine (iGEM) competition where they work in design teams to conceive of and execute a synthetic biology project that they present at an international jamboree. We surveyed the Canadian landscape of synthetic biology education through the experience of students from the Canadian iGEM teams of 2019. Using a thematic codebook analysis, we gathered insights to generate recommendations that could empower future iGEM team operations and inform educators about best practices in teaching undergraduate synthetic biology.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.019
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.923
Threshold uncertainty score0.715

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0120.019
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0040.007
Science and technology studies0.0390.012
Scholarly communication0.0140.003
Open science0.0040.011
Research integrity0.0030.006
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.234
Teacher spread0.202 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2020
Admission routes2
Has abstractyes

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