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Comparative efficacy of ceftiofur crystalline free acid and florfenicol-flunixin meglumine for undifferentiated fever treatment in feedlot calves administered tulathromycin metaphylactically on arrival

2015· article· en· W3098189257 on OpenAlexaff
Eric J. Behlke, Sherry J. Hannon, Tye Perrett, Oliver C Schunicht, Christopher A. McMullen, Brian K Wildman, R. Kent Fenton, L. O. Burciaga-Robles, M.L. May, G. Kee Jim, Sameeh M. Abutarbush, Calvin W. Booker

Bibliographic record

VenueThe Bovine Practitioner · 2015
Typearticle
Languageen
FieldImmunology and Microbiology
TopicMicrobial infections and disease research
Canadian institutionsAlberta Health Services
Fundersnot available
KeywordsCeftiofurFeedlotFlorfenicolAnimal scienceMedicineMeglumineVeterinary medicineHorseAntibioticsChemistryBiologyCephalosporinBiochemistry

Abstract

fetched live from OpenAlex

A field study was conducted at commercial feedlots to compare the relative efficacy of ceftiofur crystalline free acid (CCFA) and florfenicol-flunixin meglumine (FFM) for undifferentiated fever (UF) treatment in calves that were administered tulathromycin metaphylactically on arrival. At the time of initial diagnosis of UF, experimental calves (n=1,056) were randomly allocated to 2 experimental groups, CCFA and FFM. Calves in the CCFA group (n=530) were administered 3.0 mg/lb (6.6 mg/kg) BW of ceftiofur crystalline free acid subcutaneously (SC) at the base of the ear. Calves in the FFM group (n=526) were administered a combination of 18.1 mg/lb (40.0 mg/kg) florfenicol+1.0 mg/lb (2.2 mg/kg) flunixin meglumine SC in the neck region. The first UF relapse treatment rate was lower in the CCFA group compared to the FFM group (P=0.011). The third UF relapse treatment rate was also reduced in the CCFA group (P=0.032), but no difference was detected in the second UF relapse treatment rate between the 2 groups. No differences in overall chronicity, wastage, salvage slaughter, or mortality rates were detected between the 2 groups at the P?0.05 level. There was a net economic advantage of $10.35/treated animal in the CCFA group, driven primarily by the lower initial UF treatment cost when compared to the FFM group.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.247
Threshold uncertainty score0.539

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.089
GPT teacher head0.350
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2015
Admission routes1
Has abstractyes

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