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Record W3107254223 · doi:10.1097/cxa.0000000000000094

The Alcohol-Attributable Burden of Disease in Canada from 2000 to 2016

2020· article· en· W3107254223 on OpenAlex
Ari Franklin, Bethany R. Chrystoja, Jakob Manthey, Jürgen Rehm, Kevin D. Shield

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
venuePublished in a venue whose home country is Canada.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueThe Canadian Journal of Addiction · 2020
Typearticle
Languageen
FieldMedicine
TopicAlcohol Consumption and Health Effects
Canadian institutionsCanada Research ChairsUniversity of TorontoCentre for Addiction and Mental Health
Fundersnot available
KeywordsPer capitaAttributable riskMedicineEnvironmental healthPopulationDisease burdenDemographyBurden of diseaseAlcoholAlcohol consumptionCohortCohort studyInternal medicine

Abstract

fetched live from OpenAlex

ABSTRACT Objectives: To describe trends in Canada in alcohol consumption from 1990 to 2016, and in the alcohol-attributable burden of disease from 2000 to 2016. Methods: Alcohol consumption was measured using data from production and taxation statistics and from population surveys. Alcohol-attributable deaths and disability adjusted life years (DALYs) lost were estimated using a comparative risk assessment framework, stratified by age, sex, and cause. Relative risks were obtained from meta-analyses and cohort studies. Mortality data were obtained from the World Health Organization's Global Health Observatory. Uncertainty intervals (UIs) were estimated using Monte Carlo-like simulations. Results: From 1990 to 2016, per capita alcohol consumption in Canada decreased from 10.4L (95% UI: 10.0–10.7) to 9.0L (95% UI: 8.7–9.2). Heavy episodic drinking remained largely stable between 1990 and 2016 (an annualized 0.1% increase). In 2016, 10,556 deaths (95% UI: 8285–13,609) and 440,709 DALYs lost (95% UI: 388,853–527,260) were attributable to alcohol use. Men experienced more alcohol-attributable deaths and DALYs lost than did women, and the greatest alcohol-attributable burden was found among those over the age of 54. Alcohol-attributable age-standardized rates of deaths and DALYs lost decreased by 18.7% (95% UI: −10.2 to 25.2) and by 13.8% (95% UI: –11.4, 15.7), respectively, from 2000 to 2016. Conclusions: Despite reductions in per capita consumption and in the alcohol-attributable burden of disease, alcohol use continues to be a leading risk factor for death and disability in Canada. Accordingly, alcohol control policies should be strengthened to reduce further alcohol-attributable harms. Objectifs: Décrire les tendances de la consommation d’alcool au Canada de 1990 à 2016 et du fardeau de la maladie attribuable à l’alcool de 2000 à 2016. Méthodes: La consommation d’alcool a été mesurée à l’aide de données provenant de statistiques de production et de taxation et données d’enquêtes sur la population. Alcohol-attributable deaths and disability adjusted life years (DALYs) - les années de vie ajustées par les décès et les cas d’invalidités attribuables à l’alcool- perdues ont été estimés à l’aide d’un cadre d’évaluation comparatif des risques, et stratifié par âge, sexe et cause. Les risques relatifs ont été obtenus à partir de méta-analyses et d’études de cohorte. Les données sur la mortalité ont été obtenues auprès de l’Observatoire mondial de l’Organisation mondiale de la santé. Les intervalles d’incertitude (UI) ont été estimés à l’aide de simulations de type Monte Carlo. Résultats: De 1990 à 2016, la consommation d’alcool per capita au Canada est passée de 10,4 L (95% UI: 10.0, 10.7) à 9,0 L (95% UI: 8.7, 9.2). La consommation épisodique excessive est restée largement stable entre 1990 et 2016 (une augmentation annualisée de 0.1%). En 2016, 10 556 décès (95% UI: 8 285, 13 609) et 440 709 DALYs perdus (95% UI: 388 853, 527 260) étaient attribuables à la consommation d’alcool. Les hommes ont connu plus de décès et de DALYs perdus attribuables à l’alcool que les femmes, et le fardeau le plus lourd attribuable à l’alcool a été constaté chez les personnes de plus de 54 ans. Les taux de décès normalisés selon l’âge attribuables à l’alcool et de DALYs perdus ont diminué de 18,7% (95%UI: -10.2, 25.2) et de 13,8% (95% UI: -11.4, 15.7), respectivement, de 2000 à 2016. Conclusions: Malgré les réductions de la consommation per capita et du fardeau de la maladie attribuable à l’alcool, la consommation d’alcool continue d’être l’un des principaux facteurs de risque de décès et d’incapacité au Canada. En conséquence, les politiques de contrôle de l’alcool devraient être renforcées afin de réduire davantage les méfaits attribuables à l’alcool.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.419
Threshold uncertainty score0.989

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.288
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it