Do obese patients with primary knee osteoarthritis benefit from a single bout of moderate intensity aerobic exercise?
Bibliographic record
Abstract
Abstract Background Obesity and osteoarthritis are often concomitant. Both are accompanied by oxidative stress and stimulated inflammatory response. Exercise is considered a substantial treatment in rehabilitation of both conditions. Yet most of literature reported the benefits of regular exercising, while there is paucity about the effects of single low to moderate exercise session. This study aimed to investigate the possible potential effects of a single bout of moderate exercise in obese middle-aged individuals with knee osteoarthritis (KOA). Results Score of pain and Western Ontario and Mc-Master University (WOMAC) had been improved 24 h after exercise. Glutathione reductase (GR) activity increased post-exercise but decreased the next 24 h though remained higher than baseline. Blood glucose level was reduced post-exercise whereas blood lipids still uninfluenced by exercise. Markers of inflammation remained unchanged after exercise session. Conclusion A single bout moderate-intensity aerobic exercise is effective in improving pain and antioxidant activity among middle-aged obese patients with primary knee OA. Single bout of mild to moderate exercise may help in treatment of obese patients with KOA. Trial registration Clinical Trials.gov Identifier: NCT03927339
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".