Bibliographic record
Abstract
A 27-year-old woman presented with dyspnea and chest pain. Computed tomography scan showed an 18 cm anterior mediastinal mass compressing the heart and left lung, with tracheal deviation and chest wall extension. There was complete left lung atelectasis and a pleural effusion occupying the entire hemithorax (Panel A). Positron-emission tomography (PET) scan showed the mass contiguous with a circumferentially-thickened left pleura, with images highlighting the PET-avidity of this disease (Panels B and C). Biopsy of the mediastinal mass revealed a diffuse infiltrate of CD20-positive large B-cells confirming a diagnosis of primary mediastinal large B-cell lymphoma (PMBCL). She was treated with six cycles of dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (DA-EPOCH-R). End-of-treatment PET showed a complete metabolic response (Panel D). PMBCL is an aggressive non-Hodgkin lymphoma typically presenting in adults aged 20-50, with female predominance. Urgent immunochemotherapy is indicated in patients with life-threatening compression of thoracic structures and is potentially curative. Diego Villa and Laurie H. Sehn have received institutional research funding and honoraria from Roche. Diego Villa and Laurie H. Sehn wrote the paper. Authors have obtained written and verbal informed consent from the patient.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".