BREAST GIANT FIBROADENOMA WITH VASCULAR STROMA AND RECURRENCE AS MALIGNANT PHYLLODES TUMOR
Bibliographic record
Abstract
The stroma of fibroadenoma and phyllodes tumor consists of fibroblas-tic proliferation. Rarely the stroma contains bundles of smooth muscle. Vascular stroma is not a feature of fibroadenoma. We report a case of a 34-year old Chinese woman presented with a huge mass occupying much of the entire left breast. Left mastectomy was performed and showed a large well-circumscribed lobulated rubbery firm tumor measure 13x10x6cm. Microscopic examination revealed a remarKable neoplasm in a form of fibroepithelial tumor formed by an organoid pattern of ductal structures with very striking stromal appearance composed of extensive vascular proliferation throughout the tumor confirmed by strong immunoreaction for the endothelial cell markers CD31, CD34 and factor VIII. Ultra-structural examination confirm the endothelial nature of the lining of the vascular channels in the stroma which showed spindle cells with intercellular junctions, Basal lamina, Pinocytotic vesicles and some weibel-Palade bodies. Those finding rule out the diagnosis of pseudoangiomatous hy-perpiasia. The patient developed a local recurrence few months latter and the resection showed a malignant phyllodes tumor with ductal carcinoma in situ.In conclusion we described the first reported case of a unique giant fibroadenoma with abnormal vascular proliferation with recurrence as malignant phyllodes tumor associated
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".