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Record W3114147750 · doi:10.3389/fonc.2020.593192

Canadian Pediatric Neuro-Oncology Standards of Practice

2020· article· en· W3114147750 on OpenAlexaffabout
Julie Bennett, Craig Erker, Lucie Lafay‐Cousin, Vijay Ramaswamy, Juliette Hukin, Magimairajan Vanan, Sylvia Cheng, Hallie Coltin, Adriana Fonseca, Donna L. Johnston, Andrea Lo, Shayna Zelcer, Saima Alvi, Lynette Bowes, Josée Brossard, Janie Charlebois, David D. Eisenstat, Kathleen Felton, Adam Fleming, Nada Jabado, Valérie Larouche, Geneviève Legault, Chris Mpofu, Sébastien Perreault, Mariana Silva, Roona Sinha, Doug Strother, Derek S. Tsang, Beverly Wilson, Bruce Crooks, Ute Bartels

Bibliographic record

VenueFrontiers in Oncology · 2020
Typearticle
Languageen
FieldMedicine
TopicGlioma Diagnosis and Treatment
Canadian institutionsPrincess Margaret Cancer CentreQueen's UniversityCentre Hospitalier Universitaire Sainte-JustineCentre hospitalier universitaire de QuébecMontreal Children's HospitalCentre Hospitalier Universitaire de SherbrookeSaskatchewan Cancer AgencyMcMaster Children's HospitalLondon Health Sciences CentreChildren's Hospital of Eastern OntarioBC Children's HospitalBC Cancer AgencyStollery Children's HospitalAlberta Children's HospitalIzaak Walton Killam Health CentreUniversity of ManitobaMemorial University of NewfoundlandHospital for Sick Children
Fundersnot available
KeywordsMedicineClinical PracticePediatric oncologyClinical trialStandard of careCancerFamily medicineIntensive care medicineInternal medicine

Abstract

fetched live from OpenAlex

Primary CNS tumors are the leading cause of cancer-related death in pediatrics. It is essential to understand treatment trends to interpret national survival data. In Canada, children with CNS tumors are treated at one of 16 tertiary care centers. We surveyed pediatric neuro-oncologists to create a national standard of practice to be used in the absence of a clinical trial for seven of the most prevalent brain tumors in children. This allowed description of practice across the country, along with a consensus. This had a multitude of benefits, including understanding practice patterns, allowing for a basis to compare in future research and informing Health Canada of the current management of patients. This also allows all children in Canada to receive equivalent care, regardless of location.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.013
metaresearch head score (Gemma)0.063
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.938
Threshold uncertainty score0.453

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0130.063
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0050.008
Science and technology studies0.0050.002
Scholarly communication0.0040.002
Open science0.0050.003
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0170.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.312
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations39
Published2020
Admission routes2
Has abstractyes

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