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External Validation of a Periodontal Prediction Model for Identification of Diabetes among Saudi Adults

2020· article· en· W3120779990 on OpenAlexaboutno aff
Arwa Talakey, Francis J. Hughes, Eduardo Bernabé

Bibliographic record

VenueThe Journal of Contemporary Dental Practice · 2020
Typearticle
Languageen
FieldDentistry
TopicOral microbiology and periodontitis research
Canadian institutionsnot available
Fundersnot available
KeywordsDiabetes mellitusMedicineIdentification (biology)Clinical significanceInternal medicine

Abstract

fetched live from OpenAlex

Aim and objective: To externally validate the performance of a novel periodontal prediction model (PPM) for identification of diabetes among Saudi adults. Materials and methods:The study was carried out among 150 adults attending primary care clinics in Riyadh (Saudi Arabia).The study adopted a temporal external validation approach, where the performance of the PPM was evaluated in the same location as the development study, but at a later time to allow for some variation between samples.A case-control approach was adopted, where diabetes status was first ascertained, followed by the completion of the Finnish Diabetes Risk Score (FINDRISC), Canadian Diabetes Risk (CANRISK) tools, and periodontal examinations.Results: The area under the curve (AUC) of the PPM (based on the number of missing teeth, the proportion of sites with pocket probing depth ≥ 6 mm, and mean pocket probing depth) was 0.514 (95% CI: 0.385, 0.642).The FINDRISC and CANRISK tools had AUC values of 0.871 (95% CI: 0.811-0.931)and 0.927 (95% CI: 0.884-0.971),respectively.The addition of the PPM did not improve the AUC of FINDRISC (p = 0.479) or CANRISK (p = 0.920).The decision curve analysis showed that there was no clinical benefit in adding the PPM to either tool.The PPM was updated with an overall adjustment factor for all existing predictors and three more periodontal measures.Conclusion: In an external sample, the PPM had poor performance for identification of diabetes and no added value when combined with FINDRISC and CANRISK.The performance of the PPM improved after recalibration and extension. Clinical significance:The results underscore the value of externally validating prediction models before applying them in clinical dental practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.021
metaresearch head score (Gemma)0.039
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.021
Threshold uncertainty score0.113

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0210.039
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.311
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2020
Admission routes1
Has abstractyes

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