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Record W3121665922 · doi:10.1097/mci.0b013e32831dae43

Breastfeeding and allergies: time for a change in paradigm?

2008· article· en· W3121665922 on OpenAlexaff
Joanne Duncan, Malcolm R. Sears

Bibliographic record

VenueCurrent Opinion in Internal Medicine · 2008
Typearticle
Languageen
FieldMedicine
TopicBreastfeeding Practices and Influences
Canadian institutionsMcMaster University
Fundersnot available
KeywordsBreastfeedingAllergyMedicineEnvironmental healthPediatricsImmunology

Abstract

fetched live from OpenAlex

For decades, conventional wisdom and much medicalliterature have stated that breastfeeding, in addition toitsnutritionalandsociologicalbenefits,providedanumberofspecifichealthbenefitstotheinfant,includingreductionof the incidence of allergy and childhood wheezing. In2004,KempandKakakios[1]wrote‘Ithasbeenanarticleof faith amongst pediatricians and allergists that breast-feedingisbeneficialforthepreventionofallergicdisease’.Now that paradigm is beingchallenged, as several studiespublished over the last few years suggest, there is nosustained protective effect, or even, that there is anincreased long-term risk of allergy and asthma associatedwith breastfeeding. These reports contrast with studiesdemonstratingreductionofchildhoodwheezingandaller-gic diseases among breastfed children, leading to contro-versy and debate [2,3]. A recent editorial in the BritishMedical Journal concluded ‘...the claim that breastfeed-ingreducestheriskofallergyandasthmaisnotsupportedby evidence’ [4 ]. This review examines reasons for theconflicting reports and suggests an over-arching perspect-ive given recent evidence.Breastfeeding is a natural phenomenon, providingbalanced nutrition and mother–infant bonding, as wellas a number of health benefits. These include reducedincidence of infectious diseases, including diarrheal dis-eases and lower respiratory tract infections, reducedincidence of diabetes and obesity, and improved mentalperformance [5,6]. There are numerous reasons whybreastfeeding should be encouraged wherever possible,with few exceptions such as in the presence of maternalHIV infection [7].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.214
Threshold uncertainty score0.527

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.131
GPT teacher head0.399
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2008
Admission routes1
Has abstractyes

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