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Comparación de la inyección intraarticular de plasma rico en plaquetas (PRGF®) y ácido hialurónico (Hyalone®) en el tratamiento de las lesiones condrales: estudio clínico prospectivo aleatorizado

2021· article· es· W3122096021 on OpenAlexaboutno aff
José María Lamo-Espinosa, Martín Iglesias Curras, Andrés Valentí-Azcárate, Juan Ramón Valentí-Nin

Bibliographic record

VenueRevista Española de Artroscopia y Cirugía Articular · 2021
Typearticle
Languagees
FieldMedicine
TopicShoulder Injury and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineWOMACOsteoarthritisGynecologyPathology

Abstract

fetched live from OpenAlex

Objetivo: comparar el efecto de la inyección intraarticular de plasma rico en plaquetas (PRGF®) y ácido hialurónico (Hyalone®) en el tratamiento de las lesiones degenerativas del cartílago de la rodilla. Métodos: estudio prospectivo, aleatorizado y abierto, que compara el efecto clínico del tratamiento con PRP (PRGF®) y ácido hialurónico (Hyalone®) en pacientes con lesiones condrales degenerativas (no traumáticas) de rodilla. Se incluyeron 80 pacientes y se aleatorizaron en 2 grupos de 40 pacientes cada uno. La valoración clínica se realizó inicialmente y a los 6 meses del tratamiento mediante las escalas Knee Injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) y la escala visual analógica (EVA). Resultados: en ambos grupos se produjeron mejorías significativas respecto de los valores basales. Los pacientes tratados con PRP mejoraron en la valoración del dolor por la EVA con respecto al grupo AH, mostrando unas mejorías de 2,08 (1,5) y 0,47 (1,7), respectivamente (PRGF® vs. Hyalone®; p = 0,001). Sin embargo, no se apreciaron diferencias entre ambos grupos tanto en el WOMAC como en la escala KOOS (p > 0,05). Conclusiones: la inyección intraarticular de PRP no mostró una mejoría clínica consistente respecto al tratamiento con AH a los 6 meses de seguimiento. Aunque se observaron diferencias favorables en la EVA, estas no se tradujeron en el resto de las escalas evaluadas. Nivel de evidencia: IV.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.325
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2021
Admission routes1
Has abstractyes

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