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Record W3122860141 · doi:10.1097/bto.0000000000000514

Intramedullary Delivery of Local Antibiotics Via Calcium Sulfate Beads for Chronic Osteomyelitis With a Simple, Novel Surgical Technique

2021· article· en· W3122860141 on OpenAlexaff
Johnathan R. Lex, Jay Toor, Hayley E.M. Spurr, Jean-Philippe Cloutier, Hans J. Kreder

Bibliographic record

VenueTechniques in Orthopaedics · 2021
Typearticle
Languageen
FieldMedicine
TopicOrthopedic Infections and Treatments
Canadian institutionsHealth Sciences CentreSunnybrook Health Science CentreUniversity of Toronto
Fundersnot available
KeywordsMedicineIntramedullary rodMedullary cavitySurgeryDebridement (dental)FemurOsteomyelitisAnatomy

Abstract

fetched live from OpenAlex

Aim: The aim of this manuscript was to describe a novel surgical technique that can be used intraoperatively to aid in the management of chronic diaphyseal osteomyelitis through the delivery of antibiotics into the medullary canal. Technique: Following standard intramedullary and reamer irrigator aspirator preparation of the femoral canal, a negative-pressure gradient is created through the canal. A 32-Fr chest tube is placed antegrade down the femur and used as a conduit for delivering antibiotic beads. A 20-Fr chest tube can be used to manually piston the beads further down the canal. Uses, Outcomes, and Pitfalls: This technique can be used to administer prefabricated calcium sulfate antibiotic beads or hand-made antibiotic polymethylmethacrylate beads evenly throughout the medullary canal of long-bones. It is a simple, cost-effective, one-surgery solution to assist clinicians when managing patients presenting with this difficult problem.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.876
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.288
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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