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Record W3123380744 · doi:10.1186/s13643-021-01670-0

The REPRISE project: protocol for an evaluation of REProducibility and Replicability In Syntheses of Evidence

2021· article· en· W3123380744 on OpenAlexafffund
Matthew J. Page, David Moher, Fiona Fidler, Julian P. T. Higgins, Sue Brennan, Neal Haddaway, Daniel G. Hamilton, Raju Kanukula, Sathya Karunananthan, Lara Maxwell, Steve McDonald, Shinichi Nakagawa, David Nunan, Peter Tugwell, Vivian Welch, Joanne E. McKenzie

Bibliographic record

VenueSystematic Reviews · 2021
Typearticle
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsOttawa HospitalBruyèreUniversity of Ottawa
FundersNational Institute for Health Research Applied Research Collaboration WestNational Health and Medical Research CouncilAustralian Research CouncilUniversity of BristolDepartment of Health and Social CareNational Institute for Health and Care ResearchAustralian GovernmentNIHR Bristol Biomedical Research CentreUniversity Hospitals Bristol NHS Foundation TrustMedical Research CouncilUniversity of Ottawa
KeywordsMedicineRepriseProtocol (science)ReproducibilityAlternative medicineChromatographyPathologyHumanities

Abstract

fetched live from OpenAlex

BACKGROUND: Investigations of transparency, reproducibility and replicability in science have been directed largely at individual studies. It is just as critical to explore these issues in syntheses of studies, such as systematic reviews, given their influence on decision-making and future research. We aim to explore various aspects relating to the transparency, reproducibility and replicability of several components of systematic reviews with meta-analysis of the effects of health, social, behavioural and educational interventions. METHODS: The REPRISE (REProducibility and Replicability In Syntheses of Evidence) project consists of four studies. We will evaluate the completeness of reporting and sharing of review data, analytic code and other materials in a random sample of 300 systematic reviews of interventions published in 2020 (Study 1). We will survey authors of systematic reviews to explore their views on sharing review data, analytic code and other materials and their understanding of and opinions about replication of systematic reviews (Study 2). We will then evaluate the extent of variation in results when we (a) independently reproduce meta-analyses using the same computational steps and analytic code (if available) as used in the original review (Study 3), and (b) crowdsource teams of systematic reviewers to independently replicate a subset of methods (searches for studies, selection of studies for inclusion, collection of outcome data, and synthesis of results) in a sample of the original reviews; 30 reviews will be replicated by 1 team each and 2 reviews will be replicated by 15 teams (Study 4). DISCUSSION: The REPRISE project takes a systematic approach to determine how reliable systematic reviews of interventions are. We anticipate that results of the REPRISE project will inform strategies to improve the conduct and reporting of future systematic reviews.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.370
metaresearch head score (Gemma)0.551
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Reproducibility · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.630
Threshold uncertainty score0.777

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.3700.551
Meta-epidemiology (narrow)0.0080.009
Meta-epidemiology (broad)0.0110.011
Bibliometrics0.0130.016
Science and technology studies0.0060.011
Scholarly communication0.0120.010
Open science0.0060.009
Research integrity0.0100.016
Insufficient payload (model declined to judge)0.1500.041

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.958
GPT teacher head0.674
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designObservational
DomainReproducibility
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations56
Published2021
Admission routes2
Has abstractyes

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