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The REPRISE project: protocol for an evaluation of REProducibility and Replicability In Syntheses of Evidence

2021· article· en· 56 citations· W3123380744 on OpenAlex· 10.1186/s13643-021-01670-0

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Full frame distilled prediction

Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

Candidate categories
Metaresearch
Consensus categories
Metaresearch
Domain
Candidate signal: noneConsensus signal: none
Study design
Candidate signal: Systematic reviewConsensus signal: Systematic review
Genre
Candidate signal: ProtocolConsensus signal: Protocol
Teacher disagreement score
0.332
Threshold uncertainty score
0.448
Validation status
machine_predicted_unvalidated · codex-gemma-dda1882f352a

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.8170.897
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0070.001
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.958
GPT teacher head0.674
Teacher spread
0.285 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

BACKGROUND: Investigations of transparency, reproducibility and replicability in science have been directed largely at individual studies. It is just as critical to explore these issues in syntheses of studies, such as systematic reviews, given their influence on decision-making and future research. We aim to explore various aspects relating to the transparency, reproducibility and replicability of several components of systematic reviews with meta-analysis of the effects of health, social, behavioural and educational interventions. METHODS: The REPRISE (REProducibility and Replicability In Syntheses of Evidence) project consists of four studies. We will evaluate the completeness of reporting and sharing of review data, analytic code and other materials in a random sample of 300 systematic reviews of interventions published in 2020 (Study 1). We will survey authors of systematic reviews to explore their views on sharing review data, analytic code and other materials and their understanding of and opinions about replication of systematic reviews (Study 2). We will then evaluate the extent of variation in results when we (a) independently reproduce meta-analyses using the same computational steps and analytic code (if available) as used in the original review (Study 3), and (b) crowdsource teams of systematic reviewers to independently replicate a subset of methods (searches for studies, selection of studies for inclusion, collection of outcome data, and synthesis of results) in a sample of the original reviews; 30 reviews will be replicated by 1 team each and 2 reviews will be replicated by 15 teams (Study 4). DISCUSSION: The REPRISE project takes a systematic approach to determine how reliable systematic reviews of interventions are. We anticipate that results of the REPRISE project will inform strategies to improve the conduct and reporting of future systematic reviews.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

The record

Venue
Systematic Reviews
Topic
Meta-analysis and systematic reviews
Field
Decision Sciences
Canadian institutions
Ottawa HospitalBruyèreUniversity of Ottawa
Funders
National Institute for Health Research Applied Research Collaboration WestNational Health and Medical Research CouncilAustralian Research CouncilUniversity of BristolDepartment of Health and Social CareNational Institute for Health and Care ResearchAustralian GovernmentNIHR Bristol Biomedical Research CentreUniversity Hospitals Bristol NHS Foundation TrustMedical Research CouncilUniversity of Ottawa
Keywords
MedicineRepriseProtocol (science)ReproducibilityAlternative medicineChromatographyPathologyHumanities
Has abstract in OpenAlex
yes