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Record W3125542913 · doi:10.1038/s41746-020-00369-1

Deep COVID DeteCT: an international experience on COVID-19 lung detection and prognosis using chest CT

2021· article· en· W3125542913 on OpenAlexaff
Edward H. Lee, Jimmy Zheng, Errol Colak, Maryam Mohammadzadeh, Golnaz Houshmand, Nicholas Bevins, Felipe Kitamura, Emre Altınmakas, Eduardo Pontes Reis, Jae-Kwang Kim, Chad Klochko, Michelle Han, Sadegh Moradian, Ali Mohammadzadeh, Hashem Sharifian, Hassan Hashemi, Kavous Firouznia, Hossien Ghanaati, Masoumeh Gity, Hakan Doğan, Hojjat Salehinejad, Henrique Alves, Jayne Seekins, Nitamar Abdala, Çetin Atasoy, Hamidreza Pouraliakbar, Majid Maleki, S.S. Wong, Kristen W. Yeom

Bibliographic record

Venuenpj Digital Medicine · 2021
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 diagnosis using AI
Canadian institutionsUniversity of Toronto
FundersSociedade Beneficente Israelita Brasileira Albert Einstein
KeywordsCoronavirus disease 2019 (COVID-19)PneumoniaMedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Receiver operating characteristicConvolutional neural network2019-20 coronavirus outbreakComputed tomographyRadiologyDiseaseArtificial intelligenceComputer scienceInternal medicinePathologyInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

The Coronavirus disease 2019 (COVID-19) presents open questions in how we clinically diagnose and assess disease course. Recently, chest computed tomography (CT) has shown utility for COVID-19 diagnosis. In this study, we developed Deep COVID DeteCT (DCD), a deep learning convolutional neural network (CNN) that uses the entire chest CT volume to automatically predict COVID-19 (COVID+) from non-COVID-19 (COVID-) pneumonia and normal controls. We discuss training strategies and differences in performance across 13 international institutions and 8 countries. The inclusion of non-China sites in training significantly improved classification performance with area under the curve (AUCs) and accuracies above 0.8 on most test sites. Furthermore, using available follow-up scans, we investigate methods to track patient disease course and predict prognosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.441
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.371
Teacher spread0.315 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations51
Published2021
Admission routes1
Has abstractyes

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