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Record W3126263844 · doi:10.1093/europace/euaa279

Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference

2020· article· en· W3126263844 on OpenAlex
Larissa Fabritz, Harry J.G.M. Crijns, Eduard Guasch, Andreas Goette, Karl Georg Häusler, Dipak Kotecha, Thorsten Lewalter, Christian Meyer, Tatjana Potpara, Michiel Rienstra, Renate B. Schnabel, Stephan Willems, G Breithardt, A. John Camm, Anthony K.C. Chan, Winnie Chua, Mirko De Melis, Christina Dimopoulou, Dobromir Dobrev, Christina Easter, Lars Eckardt, Doreen Haase, Stéphane Hatem, Jeff S. Healey, Jordi Heijman, Stefan H. Hohnloser, Thomas Huebner, Bushra Saeed Ilyas, Aaron Isaacs, Ingo Kutschka, Christophe Leclercq, Gregory Y.H. Lip, Elena Andreassi Marinelli, José Luís Merino, Lluı́s Mont, Michael Näbauer, Jonas Oldgren, Helmut Pürerfellner, Ursula Ravens, Irina Savelieva, Moritz F. Sinner, Alice Sitch, Rüdiger Smolnik, Jan Steffel, Kenneth M. Steín, Monika Stoll, Emma Svennberg, Dierk Thomas, Isabelle C. Van Gelder, Burcu Vardar, Reza Wakili, Mattias Wieloch, Stef Zeemering, Paul Ziegler, Hein Heidbüchel, Gerhard Hindricks, Ulrich Schotten, Paulus Kirchhof

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEP Europace · 2020
Typearticle
Languageen
FieldMedicine
TopicAtrial Fibrillation Management and Outcomes
Canadian institutionsPopulation Health Research Institute
FundersNational Institute for Health and Care ResearchKompetenznetz Vorhofflimmern
KeywordsAtrial fibrillationMedicineRisk stratificationRisk assessmentIntensive care medicineImplantable loop recorderInternal medicine

Abstract

fetched live from OpenAlex

AIMS: The risk of developing atrial fibrillation (AF) and its complications continues to increase, despite good progress in preventing AF-related strokes. METHODS AND RESULTS: This article summarizes the outcomes of the 7th Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA) held in Lisbon in March 2019. Sixty-five international AF specialists met to present new data and find consensus on pressing issues in AF prevention, management and future research to improve care for patients with AF and prevent AF-related complications. This article is the main outcome of an interactive, iterative discussion between breakout specialist groups and the meeting plenary. AF patients have dynamic risk profiles requiring repeated assessment and risk-based therapy stratification to optimize quality of care. Interrogation of deeply phenotyped datasets with outcomes will lead to a better understanding of the cardiac and systemic effects of AF, interacting with comorbidities and predisposing factors, enabling stratified therapy. New proposals include an algorithm for the acute management of patients with AF and heart failure, a call for a refined, data-driven assessment of stroke risk, suggestions for anticoagulation use in special populations, and a call for rhythm control therapy selection based on risk of AF recurrence. CONCLUSION: The remaining morbidity and mortality in patients with AF needs better characterization. Likely drivers of the remaining AF-related problems are AF burden, potentially treatable by rhythm control therapy, and concomitant conditions, potentially treatable by treating these conditions. Identifying the drivers of AF-related complications holds promise for stratified therapy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.364

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.341
Teacher spread0.304 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it