MétaCan
Menu
Back to cohort
Record W3127885971 · doi:10.1113/ep089176

Temporal changes in pulmonary gas exchange efficiency when breath‐hold diving below residual volume

2021· article· en· W3127885971 on OpenAlexafffund
Alexander Patrician, Boris Spajić, Christopher Gasho, Hannah G. Caldwell, Tony G. Dawkins, Mike Stembridge, Andrew T. Lovering, Geoff B. Coombs, Connor A. Howe, Otto Barak, Ivan Drviš, Željko Dujić, Philip N. Ainslie

Bibliographic record

VenueExperimental Physiology · 2021
Typearticle
Languageen
FieldMedicine
TopicCardiovascular and Diving-Related Complications
Canadian institutionsUniversity of British Columbia, Okanagan CampusUniversity of British Columbia
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsMedicineCardiologyPulmonary arteryPulmonary complianceSpirometryAnesthesiaLung volumesInternal medicineLung

Abstract

fetched live from OpenAlex

New Findings What is the central question of this study? How does deep breath‐hold diving impact cardiopulmonary function, both acutely and over the subsequent 2.5 hours post‐dive? What is the main finding and its importance? Breath‐hold diving, to depths below residual volume, is associated with acute impairments in pulmonary gas exchange, which typically resolve within 2.5 hours. These data provide new insight into the behaviour of the lungs and pulmonary vasculature following deep diving. Abstract Breath‐hold diving involves highly integrative and extreme physiological responses to both exercise and asphyxia during progressive elevations in hydrostatic pressure. Over two diving training camps (Study 1 and 2), 25 breath‐hold divers (recreational to world‐champion) performed 66 dives to 57 ± 20 m (range: 18–117 m). Using the deepest dive from each diver, temporal changes in cardiopulmonary function were assessed using non‐invasive pulmonary gas exchange (indexed via the O 2 deficit), ultrasound B‐line scores, lung compliance and pulmonary haemodynamics at baseline and following the dive. Hydrostatically induced lung compression was quantified in Study 2, using spirometry and lung volume measurement, enabling each dive to be categorized by its residual volume (RV)‐equivalent depth. From both studies, pulmonary gas exchange inefficiency – defined as an increase in O 2 deficit – was related to the depth of the dive ( r 2 = 0.345; P < 0.001), with dives associated with lung squeeze symptoms exhibiting the greatest deficits. In Study 1, although B‐lines doubled from baseline ( P = 0.027), cardiac output and pulmonary artery systolic pressure were unchanged post‐dive. In Study 2, dives with lung compression to ≤RV had higher O 2 deficits at 9 min, compared to dives that did not exceed RV (24 ± 25 vs. 5 ± 8 mmHg; P = 0.021). The physiological significance of a small increase in estimated lung compliance post‐dive (via decreased and increased/unaltered airway resistance and reactance, respectively) remains equivocal. Following deep dives, the current study highlights an integrated link between hydrostatically induced lung compression and transient impairments in pulmonary gas exchange efficiency.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.783
Threshold uncertainty score0.867

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.268
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations16
Published2021
Admission routes2
Has abstractyes

Explore more

Same venueExperimental PhysiologySame topicCardiovascular and Diving-Related ComplicationsFrench-language works237,207