The Physiological Burden of the 6-Minute Walk Test Compared With Cardiopulmonary Exercise Stress Test in Patients With Severe Aortic Stenosis
Bibliographic record
Abstract
Background: Management of aortic stenosis (AS) relies on symptoms. Exercise testing is recommended for asymptomatic patients with significant AS but is often experienced as forbidding and/or technically unrealistic for patients who are often frail, deconditioned, and intimidated by the exercise test. We compared the physiological burden assessed with gas exchange assessments to gauge and respiratory exchange ratio (RER) of a 6-minute walk test (6MWT) to a cardiopul-R ESUM E Introduction : La prise en charge de la st enose aortique (SA) d epend des symptmes. L' epreuve d'effort est recommand ee aux patients asymptomatiques qui ont une SA significative, mais elle est souvent perue comme dangereuse et/ou th eoriquement irr ealiste chez ces patients qui sont souvent fragiles, en mauvaise forme et craintifs par l' epreuve d'effort. Nous avons compar e le fardeau physiologique calcul e par la consommation maximale de l'oxygne ( _ VO 2 max) et le Aortic stenosis (AS) is the most prevalent valvular disease in adults age > 65 years; 3% to 7% of this older adult population have AS. 1 Whereas medical management is generally used for those who are asymptomatic, valve replacement becomes more relevant for those with symptoms. Prognosis worsens rapidly once symptoms develop. Whereas assessment of symptoms is critical, it is not always straightforward. Patients typically have critical AS in a larger context of multimorbidity or frailty. Sedentariness and exercise intolerance are likely in most adults with severe AS because of the intrinsic effects of valvular disease and the clinical context of multimorbidity and geriatric complexities. For many AS patients, sedentary lifestyles tend to obscure symptoms.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".