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Record W3132531164 · doi:10.3324/haematol.2020.271304

Rationale for the combination of venetoclax and ibrutinib in T-prolymphocytic leukemia

2021· letter· en· W3132531164 on OpenAlexafffund
Christoph Kornauth, Charles Herbaux, Bernd Boidol, Chantal Guillemette, Patrick Caron, Marius Mayerhöfer, Stéphanie Poulain, Olivier Tournilhac, Tea Pemovska, Stephen Jun Fei Chong, Emiel van der Kouwe, Lukas Kazianka, Georg Hopfinger, Daniel Heintel, Roland Jäger, Markus Raderer, Ulrich Jäger, Ingrid Simonitsch‐Klupp, Wolfgang R. Sperr, Stefan Kubicek, Matthew S. Davids, Philipp B. Staber

Bibliographic record

VenueHaematologica · 2021
Typeletter
Languageen
FieldMedicine
TopicChronic Lymphocytic Leukemia Research
Canadian institutionsUniversité LavalCentre hospitalier de l'Université LavalCentre hospitalier universitaire de Québec
FundersNational Institutes of HealthCanadian Institutes of Health ResearchCentre hospitalier régional universitaire de LilleMedizinische Universität WienOesterreichische NationalbankUniversität WienCentre Hospitalier Universitaire de QuébecAustrian Science FundInstitut National de la Santé et de la Recherche MédicaleBroad InstituteUniversité de LilleCentre National de la Recherche ScientifiqueÖsterreichischen Akademie der WissenschaftenVienna Science and Technology FundUniversité Laval
KeywordsVenetoclaxIbrutinibProlymphocytic leukemiaMedicineLeukemiaOncologyCancer researchInternal medicineChronic lymphocytic leukemia

Abstract

fetched live from OpenAlex

International audience

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.328
Threshold uncertainty score0.995

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.311
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2021
Admission routes2
Has abstractyes

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