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Record W3135338156 · doi:10.21203/rs.3.rs-254942/v1

Structured Multidomain Cognitive Rehabilitation for Stroke: Findings From an Observational Cohort Study

2021· preprint· en· W3135338156 on OpenAlexaboutno aff
Sheng Chun Ng, Angeline Ong, Fennie Wong, Esther Vanessa Chua, Seyed Ehsan Saffari, Linda Lay Hoon Lim, Eveline Franco da Silva, Kok Pin Ng, Nagaendran Kandiah

Bibliographic record

VenueResearch Square · 2021
Typepreprint
Languageen
FieldMedicine
TopicStroke Rehabilitation and Recovery
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineGeriatric Depression ScalePhysical therapyStroke (engine)Montreal Cognitive AssessmentMoodRehabilitationCohortCognitive rehabilitation therapyObservational studyQuality of life (healthcare)CognitionFunctional Independence MeasureActivities of daily livingDepression (economics)Internal medicineClinical psychologyCognitive impairmentPsychiatryDepressive symptoms

Abstract

fetched live from OpenAlex

Abstract BackgroundPersons with mild stroke experience minimal functional difficulties; nonetheless, they are at elevated risk for post-stroke cognitive impairment (PSCI) and cognitive decline. AimsWe report outcomes from an observational cohort study of a structured, multidomain intervention for persons with mild strokes. MethodsThe Stroke Memory RehabiliTation (SMaRT) program comprises weekly two-hour group sessions for six weeks on cognitive strategies, lifestyle and relaxation. Participants were recruited from a tertiary hospital between June 2018 to September 2019. They had MRI-confirmed ischemic strokes with mild functional difficulties (modified Rankin Scale score ≤3). Participants underwent assessments and questionnaires at baseline, 1-week post-program, 3 months post-program, and 6 months post-program. Results Participants (N=108, mean age=63.54±9.22, 31.5% female) demonstrated significant improvement in cognition, mood, activities of daily living (ADL) and quality of life (QOL) (ps<0.05) across timepoints. Participants performed significantly better at 6 months post-program compared to baseline on cognitive tests (MoCA 24.47±3.22 vs. 25.80±2.83, Beta=1.26, 95% CI(0.78,1.74)), p<.001; Visual Cognitive Assessment Test (22.74±3.98 vs. 24.76±3.68, Beta=2.04, 95% CI(1.44,2.65), p<.001); 87% of participants maintained or improved in performance. At 6 months post-program, participants reported greater functional independence (Nottingham Extended ADLs Questionnaire Beta=4.20, 95% CI(2.63,5.77), p<.001); fewer depressive symptoms (Geriatric Depression Scale Beta=-1.44, 95% CI(-1.94, -0.94), p<.001); and improved QOL (Dementia-QOL Questionnaire Beta=5.28, 95% CI(1.09, 2.57), p<.001). ConclusionsThe SMaRT program is a cost-effective, scalable, structured program for PSCI. Findings suggest its potential effectiveness in reducing cognitive decline and improving other domains of well-being, with carry-over benefits after 6 months.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.015
Threshold uncertainty score0.031

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.457
Teacher spread0.352 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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