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Record W3136299772 · doi:10.1101/2021.03.22.433603

New Records of California Serogroup Virus in <i>Aedes</i> Mosquitoes and First Detection in Simulioidae Flies from Northern Canada and Alaska

2021· preprint· en· W3136299772 on OpenAlexafffundabout
Carol‐Anne Villeneuve, Kayla J. Buhler, Mahmood Iranpour, Ellen Avard, Antonia Dibernardo, Heather Fenton, Cristina M. Hansen, Géraldine-G. Gouin, Lisa L. Loseto, Emily Jenkins, L. Robbin Lindsay, Nicolas Lecomte, Patrick A. Leighton

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2021
Typepreprint
Languageen
FieldMedicine
TopicViral Infections and Vectors
Canadian institutionsFisheries and Oceans CanadaMakivik CorporationUniversity of SaskatchewanUniversité de MontréalPublic Health Agency of CanadaUniversité de Moncton
FundersFisheries and Oceans CanadaNatural Sciences and Engineering Research Council of CanadaUniversité de MontréalNetworks of Centres of Excellence of CanadaArcticNetUniversité de MonctonPolar Knowledge Canada
KeywordsAedes aegyptiArbovirusAedesGeographyEcologyBitingCulexMosquito controlBayBiologyVirusVirologyLarvaArchaeology

Abstract

fetched live from OpenAlex

Abstract An expected consequence of climate warming is an expansion of the geographic distribution of biting insects and associated arthropod-borne diseases (arboviruses). Emerging and reemerging arboviruses that can affect human health are likely to pose significant consequences for Northern communities where access to health resources is limited. In the North American Arctic, little is known about arboviruses. Thus, in 2019, we sampled biting insects in Nunavik (Kuujjuaq), Nunavut (Igloolik, Karrak Lake and Cambridge Bay), Northwest Territories (Igloolik and Yellowknife) and Alaska (Fairbanks). The main objective was to detect the presence of California serogroup viruses (CSGv) – a widespread group of arboviruses across North America and that is known to cause a wide range of symptoms, ranging from mild febrile illness to fatal encephalitis. Biting insects were captured twice daily for a 7-day period in mid-summer, using a standardized protocol consisting of 100 figure-eight movements of a sweep net. Captured specimens were separated by genus (mosquitoes) or by superfamily (other insects), and then grouped into pools of 75 by geographical locations. In total, 5079 Aedes mosquitoes and 1014 Simulioidae flies were caught. We report the detection of CSGv RNA in mosquitoes captured in Nunavut (Karrak Lake) and Nunavik (Kuujjuaq). We also report, for the first time in North America, the presence of CSGv RNA in Simulioidae flies. These results highlight the potential of biting insects for tracking any future emergence of arboviruses in the North, thereby providing key information for public health in Northern communities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.183
Threshold uncertainty score0.369

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0020.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.200
Teacher spread0.192 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes3
Has abstractyes

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