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Record W3137944384 · doi:10.1038/s41588-021-00807-0

Chromosome-scale genome assembly provides insights into rye biology, evolution and agronomic potential

2021· article· en· W3137944384 on OpenAlexafffund
M. Timothy Rabanus‐Wallace, Bernd Hackauf, Martin Mascher, Thomas Lux, Thomas Wicker, Heidrun Gundlach, Mariana Báez, Andreas Houben, Klaus Mayer, Liangliang Guo, Jesse Poland, Curtis Pozniak, Sean Walkowiak, Joanna Melonek, Coraline R. Praz, Mona Schreiber, Hikmet Budak, Matthias Heuberger, Burkhard Steuernagel, Brande B. H. Wulff, Andreas Börner, Brook Byrns, Jana Čížková, Brian Fowler, Allan K. Fritz, Axel Himmelbach, Gemy Kaithakottil, Jens Keilwagen, Beat Keller, David Konkin, Jamie Larsen, Qiang Li, Beata Myśków, Sudharsan Padmarasu, Nidhi Rawat, Uğur Sesiz, Sezgi Biyiklioglu-Kaya, Andy Sharpe, Hana Šimková, Ian Small, David Swarbreck, Helena Toegelová, Н. В. Цветкова, A. V. Voylokov, Jan Vrána, Eva Bauer, Hanna Bolibok-Brągoszewska, Jaroslav Doležel, Anthony Hall, Jizeng Jia, Viktor Korzun, André Laroche, Xuefeng Ma, Frank Ordon, Hakan Özkan, Monika Rakoczy‐Trojanowska, Uwe Scholz, Alan H. Schulman, Dörthe Siekmann, Stefan Stojałowski, Vijay Tiwari, M. Spannagl, Nils Stein

Bibliographic record

VenueNature Genetics · 2021
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicWheat and Barley Genetics and Pathology
Canadian institutionsAgriculture and Agri-Food CanadaSaskatchewan Research Council (Canada)University of Saskatchewan
FundersLeibniz-GemeinschaftAgriculture and Agri-Food CanadaDirectorate for Biological SciencesEuropean Regional Development FundGerman Network for Bioinformatics InfrastructureGrantová Agentura České RepublikyBundesministerium für Ernährung und LandwirtschaftDeutsche ForschungsgemeinschaftUniversitätsmedizin GöttingenBiotechnology and Biological Sciences Research CouncilNoble Research InstituteBundesministerium für Bildung und ForschungMontana Wheat and Barley Committee
KeywordsBiologySecaleDomesticationGenomeGermplasmIntrogressionGene poolPlant disease resistanceGeneticsChromosomeBiotechnologyGeneAgronomyGenetic diversity

Abstract

fetched live from OpenAlex

Rye (Secale cereale L.) is an exceptionally climate-resilient cereal crop, used extensively to produce improved wheat varieties via introgressive hybridization and possessing the entire repertoire of genes necessary to enable hybrid breeding. Rye is allogamous and only recently domesticated, thus giving cultivated ryes access to a diverse and exploitable wild gene pool. To further enhance the agronomic potential of rye, we produced a chromosome-scale annotated assembly of the 7.9-gigabase rye genome and extensively validated its quality by using a suite of molecular genetic resources. We demonstrate applications of this resource with a broad range of investigations. We present findings on cultivated rye's incomplete genetic isolation from wild relatives, mechanisms of genome structural evolution, pathogen resistance, low-temperature tolerance, fertility control systems for hybrid breeding and the yield benefits of rye-wheat introgressions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.214
Teacher spread0.207 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations272
Published2021
Admission routes2
Has abstractyes

Explore more

Same venueNature GeneticsSame topicWheat and Barley Genetics and PathologyFrench-language works237,207