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Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Praveen Surendran, Elena V. Feofanova, Najim Lahrouchi, Ioanna Ntalla, Savita Karthikeyan, James P. Cook, Lingyan Chen, Borbála Mifsud, Chen Yao, Aldi T. Kraja, James Cartwright, Jacklyn N. Hellwege, Ayush Giri, Vinicius Tragante, Guðmar Þorleifsson, Dajiang J. Liu, Bram P. Prins, Isobel D. Stewart, Claudia P. Cabrera, James Eales, Artur Akbarov, Paul L. Auer, Lawrence F. Bielak, Joshua C. Bis, Vickie Braithwaite, Jennifer A. Brody, E. Warwick Daw, Helen R. Warren, Fotios Drenos, Jessica D. Faul, Eric B. Fauman, Cristiano Fava, Teresa Ferreira, Christopher N. Foley, Nora Franceschini, He Gao, Olga Giannakopoulou, Franco Giulianini, Daníel F. Guðbjartsson, Xiuqing Guo, Sarah E. Harris, Aki S. Havulinna, Anna Helgadóttir, Jennifer E. Huffman, Shih‐Jen Hwang, Stavroula Kanoni, Jukka Kontto, Martin G. Larson, Ruifang Li‐Gao, Jaana Lindström, Luca A. Lotta, Yingchang Lu, Jian’an Luan, Anubha Mahajan, Giovanni Malerba, Nicholas G. D. Masca, Hao Mei, Cristina Menni, Dennis O. Mook‐Kanamori, David Mosén-Ansorena, Martina Müller‐Nurasyid, Guillaume Paré, Dirk S. Paul, Markus Perola, Alaitz Poveda, Rainer Rauramaa, Melissa A. Richard, Tom G. Richardson, Nuno Sepúlveda, Xueling Sim, Albert V. Smith, Jennifer A. Smith, James R Staley, Alena Stanáková, Patrick Sulem, Sébastien Thériault, Unnur Þorsteinsdóttir, Stella Trompet, Tibor V. Varga, Digna R. Velez Edwards, Giovanni Veronesi, Stefan Weiß, Sara M. Willems, Jie Yao, Robin Young, Bing Yu, Weihua Zhang, Jing-Hua Zhao, Wei Zhao, Εvangelos Εvangelou, Stefanie Aeschbacher, Eralda Asllanaj, Stefan Blankenberg, Lori L. Bonnycastle, Jette Bork‐Jensen, Ivan Brandslund, Peter S. Braund, Stephen Burgess, Kelly Cho, Cramer Christensen, John Connell, Renée de Mutsert, Anna F. Dominiczak, Marcus Dörr, Guðný Eiríksdóttir, Aliki‐Eleni Farmaki, J. Michael Gaziano, Niels Grarup, Megan L. Grove, Göran Hallmans, Torben Hansen, Gerardo Heiss, Marit E. Jørgensen, Eero Kajantie, Mihir Kamat, Annemari Käräjämäki, Fredrik Karpe, Heikki A. Koistinen, Csaba P. Kövesdy, Kari Kuulasmaa, Tiina Laatikainen, Lars Lannfelt, I‐Te Lee, Wen‐Jane Lee, Allan Linneberg, Lisa W. Martin, Marie Moitry, Girish N. Nadkarni, Matt J. Neville, George Papanicolaou, Oluf Pedersen, James E. Peters, Neil R Poulter, Asif Rasheed, Katrine Laura Rasmussen, Nigel W. Rayner, Reedik Mägi, Frida Renström, Rainer Rettig, Jacques E. Rossouw, Pamela J. Schreiner, Peter Sever, Tea Skaaby, Yan V. Sun, Johan Sundström, Guðmundur Þorgeirsson, Tõnu Esko, Elisabetta Trabetti, Philip S. Tsao, Stephen T. Turner, Ioanna Tzoulaki, Ilonca Vaartjes, Anne‐Claire Vergnaud, Cristen J. Willer, Peter W.F. Wilson, Daniel R. Witte, Ekaterina Yonova‐Doing, He Zhang, Naheed Aliya, Peter Almgren, Philippe Amouyel, Folkert W. Asselbergs, Michael R. Barnes, Alexandra I. F. Blakemore, Michael Boehnke, Michiel L. Bots, Erwin P. Böttinger, Julie E. Buring, John C. Chambers, Yii‐Der Ida Chen, Rajiv Chowdhury, David Conen, Adolfo Correa, George Davey Smith, Rudolf A. de Boer, Ian J. Deary, George Dedoussis, Panos Deloukas, Emanuele Di Angelantonio, Paul Elliott, Stephan B. Felix, Jean Ferrières, Ian Ford, Myriam Fornage, Paul W. Franks, Philippe Frossard, Giovanni Gambaro, Tom R. Gaunt, Vilmundur Guðnason, Tamara B. Harris, Caroline Hayward, Branwen J. Hennig, Karl‐Heinz Herzig, Erik Ingelsson, Jaakko Tuomilehto, Marjo‐Riitta Järvelin, J. Wouter Jukema, Sharon L. R. Kardia, Frank Kee, Jaspal S. Kooner, Charles Kooperberg, Lenore J. Launer, Lars Lind, Ruth J. F. Loos, Abdulla al Shafi Majumder, Markku Laakso, Mark I. McCarthy, Olle Melander, Karen L. Mohlke, Alison D. Murray, Børge G. Nordestgaard, Marju Orho‐Melander, Chris J. Packard, Sandosh Padmanabhan, Walter Palmas, Ozren Polašek, David J. Porteous, Andrew M. Prentice, Michael A. Province, Caroline L. Relton, Kenneth Rice, Paul M. Ridker, Olov Rolandsson, Frits R. Rosendaal, Jerome I. Rotter, Igor Rudan, Veikko Salomaa, Nilesh J. Samani, Naveed Sattar, Wayne H.-H. Sheu, Blair H. Smith, Nicole Soranzo, Timothy D. Spector, John M. Starr, Sylvain Sebért, Kent D. Taylor, Timo A. Lakka, Nicholas J. Timpson, Martin D. Tobin, Pim van der Harst, Peter van der Meer, Ramachandran S. Vasan, Niek Verweij, Jarmo Virtamo, Uwe Völker, David R. Weir, Eleftheria Zeggini, Fadi J. Charchar, Nicholas J. Wareham, Claudia Langenberg, Maciej Tomaszewski, Adam S. Butterworth, Mark J. Caulfield, John Danesh, Todd L. Edwards, Hilma Holm, Adriana M. Hung, Cecilia M. Lindgren, Chunyu Liu, Alisa K. Manning, Andrew P. Morris, Alanna C. Morrison, Christopher J. O’Donnell, Bruce M. Psaty, Danish Saleheen, Kāri Stefánsson, Eric Boerwinkle, Daniel I. Chasman, Daniel Levy, Christopher Newton‐Cheh, Patricia B. Munroe, Joanna M. M. Howson
Bibliographic record
VenueNature Genetics · 2021
Typeerratum
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicNutrition, Genetics, and Disease
Canadian institutionsUniversité LavalPopulation Health Research InstituteMcMaster University
FundersNovo Nordisk FondenMedical Research CouncilU.S. Department of Veterans AffairsNational Institute for Health and Care ResearchSteno Diabetes Center AarhusWellcome Trust
KeywordsBiologyMeta-analysisComputational biologyGeneticsEvolutionary biologyInternal medicineMedicine
Abstract
No abstract in any covered source. Its absence is recorded, not treated as a negative.
No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.105
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.132
Threshold uncertainty score0.442
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.007 | 0.105 |
| Meta-epidemiology (narrow) | 0.003 | 0.002 |
| Meta-epidemiology (broad) | 0.003 | 0.002 |
| Bibliometrics | 0.005 | 0.004 |
| Science and technology studies | 0.003 | 0.002 |
| Scholarly communication | 0.004 | 0.002 |
| Open science | 0.005 | 0.002 |
| Research integrity | 0.006 | 0.011 |
| Insufficient payload (model declined to judge) | 0.132 | 0.051 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
Opus teacher head0.015
GPT teacher head0.255
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".
Quick stats
Citations3
Published2021
Admission routes1
Has abstractno