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Record W3139442697 · doi:10.21203/rs.3.rs-331435/v1

Predictors and Incidence of Extubation Failure Post Modified Blalock Taussig Shunt in Infants

2021· preprint· en· W3139442697 on OpenAlexaff
Mohammed Al Ghafri, Safa Al Hadhrami, Hamid Al Badi

Bibliographic record

VenueResearch Square · 2021
Typepreprint
Languageen
FieldMedicine
TopicCongenital Heart Disease Studies
Canadian institutionsRoyal Ottawa Mental Health Centre
Fundersnot available
KeywordsMedicineShunt (medical)Incidence (geometry)CardiologyIntensive care medicine

Abstract

fetched live from OpenAlex

Abstract Objectives: To identify the characteristics of infants with extubation failure post Modified Blalock-Taussig Shunt (MBTS) and to determine the incidence and predictors of extubation failure in this group of infants and to compare it with the international figures.Methods: A single-center retrospective cohort study of infants < 1 year of age who underwent MBTS at the pediatric cardiac intensive care unit at Royal Hospital, Oman, from January 2010 to December 2019. We excluded infants who died before extubation, infants with missing data, and infants who underwent another surgical intervention before extubation. Ethical approval was obtained from the scientific research committee at the Royal Hospital. All categorical variables were presented as numbers and percentages. Analyses were performed using SPSS version 25. Results: A total of 146 infants were included in the study. Extubation failure occurred in 27 (18.5%) patients. Among those who failed extubation, 18 (66.7%) patients were ventilated before the surgery with statistically significant p-value of 0.019. A systolic blood pressure (SBP) ≤ 50th percentile was associated with extubation failure. Infants with extubation failure had longer intensive care unit length of stay and longer hospital length of stay. Severe respiratory distress and hemodynamic instability were the two main reasons for re-intubation.Conclusions: The lower incidence rate (18.5%) for extubation failure might indicate higher quality performance of our institution. Prolonged mechanical ventilation, requirements for escalation of inotropes, and SBP ≤ 50th percentile might be as predictors for extubation failure in infants post MBTS. Extubation failure is associated with longer intensive care unit and hospital admission.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.378
Teacher spread0.335 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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