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Record W3139881965

Cloning and prokaryotic expression of the full-length cDNA of CDPK gene from Leymus chinensis

2015· article· en· W3139881965 on OpenAlexaff
Cui Xi-ya

Bibliographic record

VenueJournal of the South China Agricultural University · 2015
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsScience North
Fundersnot available
KeywordsLeymusGeneBiologyComplementary DNAOpen reading framelac operonFusion proteinCloning (programming)Gene expressionEscherichia coliAmino acidMolecular cloningMolecular biologyGeneticsPeptide sequenceRecombinant DNA
DOInot available

Abstract

fetched live from OpenAlex

【Objective】Cloning and prokaryotic expression of CDPK gene from Leymus chinensis would help to further study the function of it,which could probe into its molecule mechanism how L. chinensis adapts itself to the saline-alkali habitat and provide a theoretical basis. 【Method 】 CDPK gene of L. chinensis was cloned by RT-PCR and RACE technology,which was named Lc-CDPK. By constructing prokaryotic expression vector of CDPK gene and transforming it into Escherichia coli BL21( DE3) with IPTG induction,the expression of CDPK protein was analyzed by SDS-PAGE.【Result and conclusion】The full-length c DNA sequence of CDPK gene was 1 704 bp with a 1 647 bp ORF( open reading frame)encoding 548 amino acids,and the amino acids from 81 to 339 formed the S-TKc structural domains possessing catalytic activity of serine/threonine protein kinase and having four conservative EF hand structural domains. A comparison with the nucleotide sequence of coding region of L. chinensis and those of other graminaceous crops showed that it has a close similarity with CDPK gene of wheat,sharing at identity of96%. The relative molecular mass of prokaryotic expressed fusion protein was 61 350 by IPTG induction,which matched up with the anticipated theoretical value. The induced protein reached the highest level at7 hours of induction,accounting for 49. 1% in the total bacterial proteins.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.629
Threshold uncertainty score0.169

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.161
Teacher spread0.154 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes1
Has abstractyes

Explore more

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