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Record W3140561141 · doi:10.14740/jmc2453w

General Anesthesia With Dexmedetomidine and Remifentanil in a 3-Year-Old Child: An Alternative Anesthetic Regimen to Allay Parental Concerns of the Potential Neurocognitive Effects of General Anesthesia

2016· article· en· W3140561141 on OpenAlexvenueno aff
Hina Walia, Emmett E. Whitaker, Gregory D. Pearson, Joseph D. Tobias

Bibliographic record

VenueJournal of Medical Cases · 2016
Typearticle
Languageen
FieldNeuroscience
TopicAnesthesia and Neurotoxicity Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineDexmedetomidineNeurocognitiveRemifentanilAnestheticAnesthesiaRegimenSurgeryCognitionPsychiatrySedation

Abstract

fetched live from OpenAlex

Recent attention has been focused on the potential neurocognitive effects of general anesthesia during infancy and early life. Although the exact implications of this effect have yet to be proven, media attention has been raised and parents may be aware of such problems, thereby questioning the safety of general anesthesia. Although spinal and regional anesthetic techniques have seen an increased use in an attempt to eliminate the concerns of such problems, many surgical procedures may not be amenable to regional anesthesia. We present a 3-year-old boy who presented for excision of an enlarging cyst on his left ear. During the preoperative visit with the surgeon, the patient’s mother voiced concerns regarding the potential neurocognitive effects of general anesthesia. General anesthesia was provided using a combination of dexmedetomidine and remifentanil. Previous reports of the use of this unique combination of agents are reviewed and its role in this scenario was discussed. J Med Cases. 2016;7(3):109-113 doi: https://doi.org/10.14740/jmc2453w

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.076
Threshold uncertainty score0.507

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.298
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2016
Admission routes1
Has abstractyes

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