Clinical, Laboratory, and Ultrasound Characteristics of Knee Involvement in Children With Juvenile Rheumatoid Arthritis
Bibliographic record
Abstract
Background: The aim of this study was to evaluate clinical, laboratory, and ultrasound characteristics of the knee involvement a cohort of juvenile rheumatoid arthritis patients. Methods : Nineteen JRA children with mean age of 10.2 years were recruited. Clinical assessment of the knee score was performed. Patients with a mean total score >=1 were classified as having active knee involvement. The following measurements were recorded: Ritchie articular index score , Steinbrocker grading system, and the Childhood Health Assessment Questionnaire. Visual analog scale. Laboratory investigations were performed, including complete blood count, erythrocyte sedimentation rate, C-reactive protein, and rheumatoid factor, antinuclear antibodies. Knee ultrsonography was done for both knees of all patients on the same day as the clinical and laboratory investigation. Results: Active knee group comprised 12 patients with 17 active knees. Mean Ritchie articular index score, was found to be 15.2 ± 9.6, mean of Steinbrocker grading system was 2 ± 1.2, while mean of Childhood Health Assessment Questionnaire was 1.2 ± 1.1, and that of Visual analog scale was 3.8 ± 2.4. Laboratory characteristics of patients with knee involvement showed a statistically A significant increase in ESR [54.5 ± 18.9 vs. 24.3 ± 14.8, p = 0.001] CRP levels [22.7 ± 11.4 vs. 12.6 ± 4p = 0.011], and decrease in hemoglobin concentration [9.4 ± 2.7 vs. 12.6 ± 2.4, p = 0.02]. Ultrasonography characteristics showed a statistically significant increase in knee synovial thickness and knee effusion volume. Conclusion : knee joint is considered a mirror image for the activity status of patients with JRA, with a clinical, laboratory and ultrasonic activity data consistent with the pathological profile inside the knee. doi: http://dx.doi.org/10.4021/ijcp45w
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".