Use of a one-dose subunit vaccine to prevent losses associated with porcine circovirus type 2
Bibliographic record
Abstract
In a commercial swine herd in eastern Canada, porcine circovirus associated disease (PCVAD) had been occurring for about 18 months when a test vaccine was introduced. Pigs were affected approximately 3 weeks after entering the finishing units. A total of 3852 pigs were enrolled in the study. Half of the pigs were randomly selected to be vaccinated at 19 to 59 days of age with a one-dose porcine circovirus type 2 (PCV2) vaccine (Ingelvac CircoFlex; Boehringer Ingelheim Vetmedica Inc, St Joseph, Missouri). The other half of the pigs were injected on the same day with sterile water (controls). No local or systemic adverse reactions were observed. The study pigs were placed in four different finishing units and in each one, mortality was significantly lower in vaccinated pigs (P < .01). Enlarged lymph nodes and white spots on the kidneys were among the most frequent lesions suggesting PCVAD. Splenic infarcts were observed in a few pigs. Results of two different serological tests showed that pigs could be effectively vaccinated in the presence of maternal immunity. There was no correlation between seroconversion (in response to vaccination) and protection.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".