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Record W3146280455 · doi:10.1016/j.cell.2021.02.052

Elevated rates of horizontal gene transfer in the industrialized human microbiome

2021· article· en· W3146280455 on OpenAlexaff
Mathieu Groussin, Mathilde Poyet, Ainara Sistiaga, Sean M. Kearney, Katya Moniz, Mary Noel, Jeff Hooker, Sean M. Gibbons, Laure Ségurel, Alain Froment, Rihlat Saïd-Mohamed, Alain Fezeu, Vanessa A. Juimo, Sophie Lafosse, Francis Ekwin Tabe, Catherine Girard, Deborah Iqaluk, Le Thanh Tu Nguyen, B. Jesse Shapiro, Jenni Lehtimäki, Lasse Ruokolainen, Pinja Kettunen, Tommi Vatanen, Shani Sigwazi, Audax Mabulla, Manuel Domínguez‐Rodrigo, Yvonne Ayerki Nartey, Adwoa Agyei‐Nkansah, Amoako Duah, Yaw Asante Awuku, Kenneth Valles, Shadrack Osei Asibey, Mary Afihene, Lewis R. Roberts, Amelie Plymoth, Charles Onyekwere, Roger E. Summons, Ramnik J. Xavier, Eric J. Alm

Bibliographic record

VenueCell · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGut microbiota and health
Canadian institutionsMcGill UniversityMcGill Genome CentreUniversité LavalUniversité de MontréalGovernment of NunavutMcGill University Health CentreCenter for Northern Studies
FundersH2020 Marie Skłodowska-Curie ActionsAgence Nationale de la RechercheNational Center for Advancing Translational SciencesMassachusetts Institute of Technology
KeywordsBiologyIndustrialisationMicrobiomeHorizontal gene transferHost (biology)Human microbiomeGeneGenomeEvolutionary biologyGenetics

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.015
Threshold uncertainty score0.268

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.280
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations361
Published2021
Admission routes1
Has abstractno

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