Study on cognitive function and event related potential N400 in old patients with depression
Bibliographic record
Abstract
Objective To explore the cognitive function and event related potential N400 of old patient with depression in remission.Methods Twenty-three elderly person aged 60 and over(depression group) with depression who met diagnostic criteria according to CCMD-3 and 20 elderly healthy person(control group) were investigated.All subjects were interviewed with HAMD,MMSE,MoCA and event-related potential N400 were measured.The correlation between cognition and event-related potential N400 and its diagnostic value for depression in the elderly was analyzed.Results The score of MMSE and MoCA were significantly lower in depression group than in control group(P0.05).N400 latency in depression group were significantly longer than those in control group(P0.05).N400 amplitude in depression group were significantly lower than those in control group(P0.05).The latency and amplitude of N400 significantly correlated to the score of MMSE and MoCA.Discriminant analysis found that the score of MMSE,the amplitude of Pz and the latency of C3 showed valuable in the diagnosis of senile depression.Conclusions The findings suggest that remitted senile depression patients have impairment in their cognitive function and N400.Event related potential N400 is valuable in the diagnosis of depression in the elderly.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".