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Record W3148718305 · doi:10.4021/jmc1011w

Sunitinib Induced Diffuse Alveolar Hemorrhage: A Case Report

2013· article· en· W3148718305 on OpenAlexvenueno aff
Sethi

Bibliographic record

VenueJournal of Medical Cases · 2013
Typearticle
Languageen
FieldMedicine
TopicMedical Imaging and Pathology Studies
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineSunitinibDiffuse alveolar hemorrhageBloodyPapillary renal cell carcinomasRespiratory distressBronchoalveolar lavageRenal cell carcinomaAdverse effectBronchoscopyLungRadiologyRespiratory failureNephrectomyPathologyKidneyInternal medicineSurgery

Abstract

fetched live from OpenAlex

A 68-year-old man with papillary renal cell carcinoma of the transplanted kidney presented with worsening respiratory distress while on treatment with sunitinib. Computerized tomography of chest revealed diffuse ground-glass opacities, and sequentially bloody bronchoalveolar lavage fluid was noted on bronchoscopy. There was marked clinico-radiologic improvement after withdrawal of sunitinib. This is the first case report of diffuse alveolar hemorrhage as an adverse effect of sunitinib in non-metastatic papillary renal cell carcinoma. With the increasing use of sunitinib in treatment of solid tumors, it is important to be aware of this potential adverse effect. Clinicians need to be vigilant for alveolar hemorrhage in patients on sunitinib with or without evidence of lung metastasis. J Med Cases. 2013;4(3):196-198 doi: https://doi.org/10.4021/jmc1011w

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.021
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.054
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.021
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.070
GPT teacher head0.361
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

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