Extracorporeal Membrane Oxygenation in Hyperthyroidism-Related Cardiomyopathy: Two Case Reports
Bibliographic record
Abstract
Hyperthyroidism-related cardiomyopathy complicated by acute heart failure and shock is a life-threatening condition. Due to the co-occurrence of systemic congestion, left ventricular systolic dysfunction, and reduced systemic vascular resistance, clinical management remains a major challenge in the intensive care unit. Extracorporeal membrane oxygenation (ECMO) provides temporary support in patients with refractory heart failure and cardiogenic shock. We describe two patients with severe hyperthyroidism-related cardiomyopathy. The first patient, a 33-year-old Chinese male, was newly diagnosed to have hyperthyroidism, presenting with thyroid storm and multi-organ failure. The second patient, a 35-year-old Chinese female, had relapsed Graves ’ disease complicated with hyperthyroidism-related cardiomyopathy and atrial fibrillation. Both patients developed acute heart failure and circulatory collapse, necessitating invasive hemodynamic support. They were hemodynamically supported with veno-arterial mode extracorporeal membrane oxygenation (VA-ECMO) and mechanical ventilation, which were successfully weaned off after 4 days. Subsequent echocardiography and cardiac magnetic resonance revealed normalization of the left ventricular ejection function. Hyperthyroidism-related cardiomyopathy with circulatory collapse is often a fatal condition. Given its highly reversible nature, more aggressive initial mechanical circulatory support in the form of VA-ECMO is warranted. J Endocrinol Metab. 2013;3(1-2):24-28 doi: https://doi.org/10.4021/jem144w
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.006 |
| Meta-epidemiology (narrow) | 0.004 | 0.003 |
| Meta-epidemiology (broad) | 0.002 | 0.003 |
| Bibliometrics | 0.005 | 0.003 |
| Science and technology studies | 0.004 | 0.003 |
| Scholarly communication | 0.004 | 0.004 |
| Open science | 0.003 | 0.004 |
| Research integrity | 0.012 | 0.007 |
| Insufficient payload (model declined to judge) | 0.003 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".