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Record W3151277459

Expressions of RhoC,CD44v6 and ICAM- 1 in human gastric cancer and its clinicopathological significance

2005· article· en· W3151277459 on OpenAlexaff
Zhao Zeng

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCancer-related gene regulation
Canadian institutionsCAE (Canada)
Fundersnot available
KeywordsRhoCMedicineImmunohistochemistryICAM-1MetastasisCancerInternal medicinePathologyLymphovascular invasionLymphatic systemOncologyGastroenterologyImmunologyCell adhesion molecule
DOInot available

Abstract

fetched live from OpenAlex

Objective To investigate the expressions of RhoC,CD44v6 and ICAM- 1 in gastric cancer and their correlations. Methods SABC immunohistochemistry was used to detect the expressions of RhoC,CD44v6 and ICAM- 1 in the specimens from 40 cases with gastric cancer. Their correlations were reviewed by clinicopathological data. Results The expression of RhoC,CD44v6 and ICAM- 1 were not correlated with tumor differetiation and invasion depth(P 0.05),but significantly correlated with lymph metastasis and pTNM stage(P 0.05). There was a significant correlation between the expression of RhoC and the expression of CD44v6 or ICAM- 1( r=0.355, P=0.006;r=0.354, P=0.003) respectively. If RhoC was positive- expressed,and either of CD44v6 or ICAM- 1 was positive- expressed, the sensitivity and the specificity for predicting the lymphatic metastasis was 93.75% ,62.5% respectively. Conclusions The positive expressions of RhoC,CD44v6 and ICAM- 1 are useful biological markers for predicting the metastatic potential of gastric cancer. The combined detection of three markers is a useful method for predicting lymphatic metastasis of gastric cancer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.289
Threshold uncertainty score0.306

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.313
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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