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Record W3153788217 · doi:10.1073/pnas.2013925118

Patterns of bacterial motility in microfluidics-confining environments

2021· article· en· W3153788217 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueProceedings of the National Academy of Sciences · 2021
Typearticle
Languageen
FieldEngineering
TopicMicrofluidic and Bio-sensing Technologies
Canadian institutionsPolytechnique MontréalUniversity of WaterlooMcGill University
FundersAustralian Research CouncilSocial Sciences and Humanities Research Council of CanadaNatural Sciences and Engineering Research Council of CanadaGrantová Agentura České RepublikyGovernment of CanadaAdvanced Research Projects AgencyDefense Advanced Research Projects AgencyMcGill University
KeywordsMotilityFlagellumMicrofluidicsMesoscale meteorologyNanomechanicsNanotechnologyBiological systemPhysicsBiophysicsBiologyBacteriaMaterials scienceCell biologyAtomic force microscopyMeteorology

Abstract

fetched live from OpenAlex

Significance Understanding bacterial movement is crucial for health, agriculture, environment, and industry. Studying the motility of five bacterial species in microfluidic environments showed that bacterial motility behavior is the result of a “tug-of-war” between hydrodynamics and local nanomechanics. In less confining spaces, bacterial motility is governed by hydrodynamics and can be approximately predicted by modeling developed for the simplest species. Conversely, in tightly confining environments, movement is mainly controlled by the steric interactions between flagella and the surrounding walls. Intriguingly, in mesoscale-sized geometries, hydrodynamics and bacterium–wall interactions overlap, either “constructively,” leading to smooth movement in straight channels, or “destructively,” leading to trapping. Our study provides a methodological template for the development of devices for single-cell genomics, diagnostics, or biocomputation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.082
Threshold uncertainty score0.204

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.246
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it