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Record W3156279317 · doi:10.1136/bmj.n917

Overcoming spectrum bias for accurate SARS-CoV-2 seroprevalence estimates

2021· article· en· W3156279317 on OpenAlexaff
Milo A. Puhan, Arnaud Chioléro, Jan Fehr, Stéphane Cullati

Bibliographic record

VenueBMJ · 2021
Typearticle
Languageen
FieldMedicine
TopicSARS-CoV-2 and COVID-19 Research
Canadian institutionsMcGill University
Fundersnot available
KeywordsSeroprevalenceCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Population2019-20 coronavirus outbreakHerd immunityMedicineStatisticsVirologyDemographyImmunologyEnvironmental healthMathematicsAntibodySerologyInternal medicineDisease

Abstract

fetched live from OpenAlex

Repeated population based SARS-CoV-2 seroprevalence studies provide evidence on how immunity develops in a population. They are especially relevant now, as we are at a turning point with vaccines that greatly accelerate the development of immunity. A surprisingly low seroprevalence of 14% was recently reported for the UK.1 The cumulative proportion of confirmed infected people in the UK (6.3%) is very close to that of Switzerland (6.6%).2 Assuming that only around one in 3-4 infected people are …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.105
metaresearch head score (Gemma)0.436
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.895
Threshold uncertainty score0.556

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1050.436
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0050.004
Science and technology studies0.0010.002
Scholarly communication0.0040.005
Open science0.0030.005
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0080.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.143
GPT teacher head0.426
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2021
Admission routes1
Has abstractyes

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