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Valve Academic Research Consortium 3: Updated Endpoint Definitions for Aortic Valve Clinical Research

2021· article· en· 1,218 citations· W3156434758 on OpenAlex· 10.1016/j.jacc.2021.02.038

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Classifier prediction

metacan-v1-d91a1de5be90

Predictions imitate two machine teachers. Scores are not calibrated prevalence probabilities.

Classifier candidate
ObservationalTheoretical or conceptual
Classifier consensus
ObservationalTheoretical or conceptual
Teacher imitation scores

Codex

Observational0.762
Theoretical or conceptual0.069
Metaresearch0.046
Not applicable0.016
Other design0.012
Case report0.004
Open science0.002
Bibliometrics0.002
Scholarly communication0.001
Meta-epidemiology (broad)0.001
Meta-analysis0.000
Research integrity0.000
Randomized trial0.000
Systematic review0.000
Bench or experimental0.000
Simulation or modelling0.000
Non-randomized trial0.000
Meta-epidemiology (narrow)0.000
Science and technology studies0.000
Qualitative0.000

Gemma

Observational0.904
Theoretical or conceptual0.095
Metaresearch0.019
Not applicable0.007
Case report0.006
Meta-epidemiology (broad)0.004
Bench or experimental0.001
Qualitative0.001
Research integrity0.001
Meta-analysis0.001
Bibliometrics0.000
Scholarly communication0.000
Science and technology studies0.000
Meta-epidemiology (narrow)0.000
Open science0.000
Non-randomized trial0.000
Systematic review0.000
Randomized trial0.000
Simulation or modelling0.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.189
GPT teacher head0.509
Teacher spread
0.320 how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

AIMS

The Valve Academic Research Consortium (VARC), founded in 2010, was intended to (i) identify appropriate clinical endpoints and (ii) standardize definitions of these endpoints for transcatheter and surgical aortic valve clinical trials. Rapid evolution of the field, including the emergence of new complications, expanding clinical indications, and novel therapy strategies have mandated further refinement and expansion of these definitions to ensure clinical relevance. This document provides an up…

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