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Record W3157519489 · doi:10.1113/ep089539

Exercise temperature regulation following a 35‐day horizontal bedrest

2021· article· en· W3157519489 on OpenAlexaff
Stylianos N. Kounalakis, Michail E. Keramidas, Ola Eiken, Igor B. Mekjavić

Bibliographic record

VenueExperimental Physiology · 2021
Typearticle
Languageen
FieldMedicine
TopicThermoregulation and physiological responses
Canadian institutionsSimon Fraser University
Fundersnot available
KeywordsDeconditioningIntensity (physics)ThermoregulationMedicineExercise intensityPhysical therapyInternal medicineCardiologyHeart rateBlood pressurePhysics

Abstract

fetched live from OpenAlex

New Findings What is the central question of this study? Does a 35‐day horizontal bedrest impair thermoeffector responses during whole‐body submaximal exercise performed in temperate conditions? What is the main finding and its importance? Cardiovascular and muscular deconditioning ensuing from prolonged recumbency seems to augment, at least to a degree, exercise‐induced increase in body core temperature, most likely due to an impairment in non‐evaporative heat loss. The response is a function of the absolute exercise intensity imposed. Abstract We examined the effects of a 35‐day horizontal bedrest on thermoregulation during whole‐body exercise. Fifteen healthy men were randomly assigned to either a bedrest (BR; n = 10) or a control (CON; n = 5) group. Prior to bedrest, both groups performed 40‐min constant‐load upright cycling at 30% of their peak workload ( W peak ; PRE). One and 2 days after bedrest, the BR group performed, in a randomised counterbalanced order, two 40‐min trials at 30% of (i) the pre‐bedrest W peak (i.e., at a fixed absolute intensity; POST‐A) and (ii) the post‐bedrest W peak (i.e., at a fixed relative intensity; POST‐R). The CON group conducted only the POST‐A trial, at the same time intervals. During the trials, rectal ( T rec ) and skin ( sk ) temperatures, and the forehead sweating rate (SwR) were monitored. In the CON group, no differences were observed between the trials. Bedrest potentiated moderately the T rec elevation during the latter part of POST‐A (∼0.10°C; P ≤ 0.05), but not of POST‐R (∼0.04°C; P = 0.11). In both post‐bedrest trials, sk was attenuated by ∼1.5–2.0°C throughout ( P < 0.01), whereas the forehead SwR was not modulated. T rec and sk were similar in POST‐A and POST‐R, yet the forehead SwR was more dependent on the relative workload imposed ( P = 0.04). The present findings therefore suggest that the cardiovascular and muscular deconditioning ensuing from a 35‐day bedrest may aggravate the exercise‐induced increase in body core temperature when working at a given absolute intensity, most likely due to an impairment in non‐evaporative heat loss.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.322
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.302
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes1
Has abstractyes

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