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Record W3157629980 · doi:10.1016/j.hrcr.2021.04.010

Author’s Reply—Phase-4 RBBB in Lyme carditis?

2021· article· en· W3157629980 on OpenAlexaff
Jeffrey M. Vinocur, Adrián Baranchuk

Bibliographic record

VenueHeartRhythm Case Reports · 2021
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Effects of Exercise
Canadian institutionsQueen's University
Fundersnot available
KeywordsMedicineRight bundle branch blockCardiologyInternal medicineHeart blockAtrioventricular blockLYMELeft bundle branch blockElectrocardiographyHeart failureBorrelia burgdorferi

Abstract

fetched live from OpenAlex

We are honored by Professor Belhassen’s interest in our report1Maxwell N. Dryer M.M. Baranchuk A. Vinocur J.M. Phase 4 block of the right bundle branch suggesting His-Purkinje system involvement in Lyme carditis.HeartRhythm Case Rep. 2020; 7: 112-116Abstract Full Text Full Text PDF PubMed Scopus (3) Google Scholar of Lyme carditis manifesting with high-grade atrioventricular block and intermittent late-coupled beats of right bundle branch–like morphology. We proposed that these beats were conducted with aberrancy owing to phase 4 block in the right bundle. In retrospect, perhaps we should have set out several alternatives, for as Professor Mauricio Rosenbaum used to say, “Every complex arrhythmia has at least 3 different explanations!”2Wellens H.J. Reply to the Editor - high-degree atrioventricular block in a 77-year-old man.Heart Rhythm. 2017; 14: e271Abstract Full Text Full Text PDF PubMed Scopus (1) Google Scholar,3Varriale P. Gul E.E. Ali F.S. Glover B. Baranchuk A. More about grouped beating: What's the diagnosis? The “Rosenbaum's approach to ECG diagnosis.J Electrocardiol. 2016; 49: 749-751Crossref Google Scholar Professor Belhassen hypothesizes instead that these beats are from a ventricular escape rhythm. We acknowledge the merits of this explanation, and appreciate particularly his astute observation of a very subtle fusion beat (third beat in Figure 2C). Additionally, we observe the wide beats lack typical right bundle branch block pattern as might be expected with a discrete proximal injury in an otherwise normal heart. With regard to the observation that there is no other disturbance of His-Purkinje conduction, we note the right axis deviation seen on narrow-complex beats at presentation and throughout the acute period, but absent at outpatient follow-up (not shown). This may represent transient left posterior fascicular block4Pérez-Riera A.R. Barbosa-Barros R. Daminello-Raimundo R. de Abreu L.C. Tonussi Mendes J.E. Nikusc K. Left posterior fascicular block, state-of-the-art review: A 2018 update.Indian Pacing Electrophysiol J. 2018; 18: 217-230Crossref PubMed Scopus (7) Google Scholar (seen best in Figure 3B; precordial lead placement may have been imperfect in Figure 2 owing to external pacing pads). We lack provocative maneuvers or intracardiac recordings to provide definitive resolution to this question. However, in either case, there is reason to question the integrity of the His-Purkinje system; as Professor Belhassen notes, an adolescent with atrioventricular nodal block should have a junctional escape. To the Editor—Phase-4 RBBB in Lyme carditis?HeartRhythm Case ReportsVol. 7Issue 7PreviewMaxwell and colleagues1 recently reported the case of an adolescent with Lyme carditis who exhibited high-degree atrioventricular (AV) block and “phase-4 right bundle branch block (RBBB).” Full-Text PDF Open Access

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.114
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.320
Teacher spread0.301 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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