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Record W3158319536 · doi:10.21203/rs.3.rs-433490/v1

WSSH_DR: Weakly Supervised Sensitive Heatmap Framework to Classify and Localize Diabetic Retinopathy Lesions

2021· preprint· en· W3158319536 on OpenAlexaff
Mohammed Al-Mukhtar, Ameer Morad, Mustafa Al-badri, Md. Sajedul Islam

Bibliographic record

VenueResearch Square · 2021
Typepreprint
Languageen
FieldMedicine
TopicRetinal Imaging and Analysis
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsArtificial intelligencePreprocessorDiabetic retinopathyComputer scienceFundus (uterus)SmoothingPattern recognition (psychology)Computer visionBlindnessMatching (statistics)Test setCADMedicineOphthalmologyPathologyOptometryDiabetes mellitus

Abstract

fetched live from OpenAlex

Abstract Vision loss happens due to diabetic retinopathy (DR) in severe stages. Thus, an automatic detection method applied to diagnose DR in an earlier phase may help medical doctors to make better decisions. DR is considered one of the main risks, leading to blindness. Computer-Aided Diagnosis (CAD) systems play an essential role in detecting features in fundus images. Fundus images may include blood vessel area, exudates, micro-aneurysm, hemorrhages, and neovascularization. In this paper, our model combines automatic detection for the diabetic retinopathy classification with localization methods depending on weakly-supervised learning. The model has four stages; in stage one, various preprocessing techniques are applied for smoothing the data set. In stage two, the network had gotten deeply to the optic disk segment for eliminating any exudate's false prediction because the exudates had the same color pixel as the optic disk. Stage three, the network is fed through training data to classify each class label. Finally, the layers of the convolution neural network are re-edited, and the layers are used to localize the impact of DR on the eye's patient. The framework tackled the matching technique between two essential concepts where the classification problem depends on the supervised learning method. In comparison, the localization problem was obtained by the weakly supervised method. An additional layer known as weakly supervised sensitive heat map (WSSH) was added to detect the ROI of the lesion at a test accuracy of 98.65%.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.008
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.414
Teacher spread0.346 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2021
Admission routes1
Has abstractyes

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