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Record W3159475202 · doi:10.1212/wnl.0000000000012125

APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies

2021· article· en· W3159475202 on OpenAlexfundno aff
Aykut Aytulun, Andrés Cruz-Herranz, Orhan Aktaş, Laura J. Balcer, Lisanne J. Balk, Piero Barboni, Augusto Azuara‐Blanco, Peter A. Calabresi, Fiona Costello, Bernardo Sánchez‐Dalmau, Delia Cabrera DeBuc, Nicolas Feltgen, Robert P. Finger, Jette Lautrup Frederiksen, Elliot M. Frohman, Teresa C. Frohman, David F. Garway‐Heath, Iñigo Gabilondo, Jennifer Graves, Ari Green, Hans-Peter Hartung, Joachim Havla, Frank G. Holz, Jaime Imitola, Rachel Kenney, Alexander Klistorner, Benjamin Knier, Thomas Korn, Scott Kolbe, Julia Krämer, Wolf A. Lagrèze, Letizia Leocani, Oliver Maier, Elena H. Martínez‐Lapiscina, Sven G. Meuth, Olivier Outteryck, Friedemann Paul, Axel Petzold, Gorm Pihl-Jensen, Jana Lízrová Preiningerová, Gema Rebolleda, Marius Ringelstein, Shiv Saidha, Sven Schippling, Joel S. Schuman, Robert C. Sergott, Ahmed Toosy, Pablo Villoslada, Sebastián Wolf, E. Ann Yeh, Patrick Yu‐Wai‐Man, Hanna Zimmermann, Alexander U. Brandt, Philipp Albrecht

Bibliographic record

VenueNeurology · 2021
Typearticle
Languageen
FieldEngineering
TopicOptical Coherence Tomography Applications
Canadian institutionsnot available
FundersInstituto de Salud Carlos IIIMedical Research CouncilNYU Grossman School of MedicineSUNY Downstate Medical CenterSchool of Medicine, Stanford UniversityNational Institutes of HealthMedDay PharmaceuticalsIpsenUniversity of ThessalyKing Khaled Eye Specialist HospitalAllerganNagoya City UniversityFriedrich-Baur-StiftungUniversità degli Studi di UdineUniversidad de ZaragozaGenentechUniversità di BolognaNational and Kapodistrian University of AthensMerz PharmaceuticalsUniversitetet i BergenUniversidade Federal de Minas GeraisChinese University of Hong KongUniversity of PittsburghTel Aviv UniversitySanofi GenzymeNovo NordiskLunds UniversitetElse Kröner-Fresenius-StiftungBundesministerium für Bildung und ForschungCarl Zeiss Meditec AGDeutsche ForschungsgemeinschaftHeidelberg EngineeringDeutscher Akademischer AustauschdienstSight Research UKBayer HealthCareMoorfields Eye Hospital NHS Foundation TrustArthur Arnstein StiftungNightstaRxFresenius Medical Care North AmericaSeoul National University Bundang HospitalNational Multiple Sclerosis SocietyEuropean Regional Development FundUniversitat de BarcelonaAmicus TherapeuticsIkerbasque, Basque Foundation for ScienceCanadian Institutes of Health ResearchMultiple Sclerosis Society of CanadaRace to Erase MSHospital for Sick ChildrenRosetrees TrustMylanRegeneron PharmaceuticalsUniversity of California, San FranciscoMassachusetts Eye and EarGuthy-Jackson Charitable FoundationChugai PharmaceuticalMinisterio de Ciencia e InnovaciónJohns Hopkins UniversityAarhus UniversitetFundación CellexMassachusetts Institute of TechnologyUniversität BaselAmerican University of BeirutEMD SeronoIran University of Medical SciencesOntario Institute for Regenerative MedicineResearch to Prevent BlindnessState University of New YorkYork UniversityAerie PharmaceuticalsBiogenRigshospitaletAarhus UniversitetshospitalCelgeneSeoul National UniversityApellis PharmaceuticalsAlexion PharmaceuticalsTeva Pharmaceutical IndustriesGrifolsUniversity College LondonUniversity of Southern CaliforniaNational Institute for Health and Care ResearchSanofi
KeywordsGrading (engineering)ChecklistMedical physicsTerminologyGuidelineProtocol (science)Optical coherence tomographyDelphi methodDelphiComputer scienceMedicineArtificial intelligenceRadiologyPsychologyPathologyAlternative medicine

Abstract

fetched live from OpenAlex

OBJECTIVE: To update the consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results, thus revising the previously published Advised Protocol for OCT Study Terminology and Elements (APOSTEL) recommendations. METHODS: To identify studies reporting quantitative OCT results, we performed a PubMed search for the terms "quantitative" and "optical coherence tomography" from 2015 to 2017. Corresponding authors of the identified publications were invited to provide feedback on the initial APOSTEL recommendations via online surveys following the principle of a modified Delphi method. The results were evaluated and discussed by a panel of experts and changes to the initial recommendations were proposed. A final survey was recirculated among the corresponding authors to obtain a majority vote on the proposed changes. RESULTS: A total of 116 authors participated in the surveys, resulting in 15 suggestions, of which 12 were finally accepted and incorporated into an updated 9-point checklist. We harmonized the nomenclature of the outer retinal layers, added the exact area of measurement to the description of volume scans, and suggested reporting device-specific features. We advised to address potential bias in manual segmentation or manual correction of segmentation errors. References to specific reporting guidelines and room light conditions were removed. The participants' consensus with the recommendations increased from 80% for the previous APOSTEL version to greater than 90%. CONCLUSIONS: The modified Delphi method resulted in an expert-led guideline (evidence Class III; Grading of Recommendations, Assessment, Development and Evaluations [GRADE] criteria) concerning study protocol, acquisition device, acquisition settings, scanning protocol, funduscopic imaging, postacquisition data selection, postacquisition analysis, nomenclature and abbreviations, and statistical approach. It will be essential to update these recommendations to new research and practices regularly.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.347
metaresearch head score (Gemma)0.568
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.653
Threshold uncertainty score0.805

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.3470.568
Meta-epidemiology (narrow)0.0030.006
Meta-epidemiology (broad)0.0060.017
Bibliometrics0.0290.012
Science and technology studies0.0040.005
Scholarly communication0.0130.008
Open science0.0130.013
Research integrity0.0140.013
Insufficient payload (model declined to judge)0.0100.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.096
GPT teacher head0.358
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
DomainReporting
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations220
Published2021
Admission routes1
Has abstractyes

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