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Record W3160561505 · doi:10.1002/mpr.1873

Selective cutoff reporting in studies of the accuracy of the Patient Health Questionnaire‐9 and Edinburgh Postnatal Depression Scale: Comparison of results based on published cutoffs versus all cutoffs using individual participant data meta‐analysis

2021· review· en· W3160561505 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueInternational Journal of Methods in Psychiatric Research · 2021
Typereview
Languageen
FieldMedicine
TopicMaternal Mental Health During Pregnancy and Postpartum
Canadian institutionsMcGill University Health CentreMcGill UniversityJewish General Hospital
FundersEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institute of Diabetes and Digestive and Kidney DiseasesNational Institute of Mental HealthNational Institute on Disability and Rehabilitation ResearchNational Health and Medical Research CouncilMedical Research CouncilNational Center for Medical Rehabilitation ResearchFonds de Recherche du Québec - SantéFogarty International CenterCanadian Institutes of Health ResearchInnovatiefonds ZorgverzekeraarsChina Medical UniversityFundação de Amparo à Pesquisa do Estado de Minas GeraisHealth Research Council of New ZealandNational Health Research InstitutesUniversiti Putra MalaysiaMahidol UniversityConselho Nacional de Desenvolvimento Científico e TecnológicoCenters for Disease Control and PreventionUniversity of MelbourneU.S. Department of Veterans AffairsSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungUniversität HeidelbergUniversity of AucklandUniversity of OxfordDivision of Materials ResearchNational Institute for Health and Care ResearchWellcome TrustPfizerFaculty of Medicine, McGill UniversityUniversity of WashingtonMinistry of Health, Labour and WelfareNational Institutes of HealthRobert Wood Johnson FoundationHealth Services Research and DevelopmentMcGill University Health CentreNational Institute on Minority Health and Health DisparitiesProgramme Grants for Applied ResearchMcGill UniversityAmerican Federation for Aging ResearchNational Science FoundationNational Heart, Lung, and Blood InstituteTehran University of Medical Sciences and Health ServicesIschemia Research and Education FoundationHunter Medical Research InstituteAmerican Psychological AssociationUniversity of Connecticut
KeywordsCutoffMedicineMean differencePatient Health QuestionnaireMeta-analysisBivariate analysisDepression (economics)Confidence intervalStatisticsInternal medicineDepressive symptomsPsychiatryPhysicsMathematics

Abstract

fetched live from OpenAlex

OBJECTIVES: Selectively reported results from only well-performing cutoffs in diagnostic accuracy studies may bias estimates in meta-analyses. We investigated cutoff reporting patterns for the Patient Health Questionnaire-9 (PHQ-9; standard cutoff 10) and Edinburgh Postnatal Depression Scale (EPDS; no standard cutoff, commonly used 10-13) and compared accuracy estimates based on published cutoffs versus all cutoffs. METHODS: We conducted bivariate random effects meta-analyses using individual participant data to compare accuracy from published versus all cutoffs. RESULTS: For the PHQ-9 (30 studies, N = 11,773), published results underestimated sensitivity for cutoffs below 10 (median difference: -0.06) and overestimated for cutoffs above 10 (median difference: 0.07). EPDS (19 studies, N = 3637) sensitivity estimates from published results were similar for cutoffs below 10 (median difference: 0.00) but higher for cutoffs above 13 (median difference: 0.14). Specificity estimates from published and all cutoffs were similar for both tools. The mean cutoff of all reported cutoffs in PHQ-9 studies with optimal cutoff below 10 was 8.8 compared to 11.8 for those with optimal cutoffs above 10. Mean for EPDS studies with optimal cutoffs below 10 was 9.9 compared to 11.8 for those with optimal cutoffs greater than 10. CONCLUSION: Selective cutoff reporting was more pronounced for the PHQ-9 than EPDS.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.025
metaresearch head score (Gemma)0.023
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.543
Threshold uncertainty score0.985

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0250.023
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.695
GPT teacher head0.672
Teacher spread0.023 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it