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The effect of electrical stimulation by bipolar-pulse microcurrents on regeneration processes in experiment and clinic

2019· article· en· W3161828836 on OpenAlexaboutno aff
Н. Н. Лазаренко, М.И. Шемшук, Marina Yu. Gerasimenko, Zhanna G. Tigay

Bibliographic record

VenueRussian Journal of Physiotherapy Balneology and Rehabilitation · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlanarian Biology and Electrostimulation
Canadian institutionsnot available
Fundersnot available
KeywordsStimulationMedicineScarsPlaceboSurgeryHypertrophic scarsAnesthesiaInternal medicinePathology

Abstract

fetched live from OpenAlex

Objective. The purpose of this study is to study the effect of electrical stimulation by bipolar-pulsed microcurrents: in an experiment on lymphatic drainage of a marker from the mesentery of mice and in the clinic on patients with hypertrophic scars in the face. Materials and methods. In the experiment, the rate of resorption of the marker from the mesentery of mice (n = 10) receiving the placebo procedure and mice (n = 10) receiving the course of electrical stimulation with bipolar-pulsed microcurrents were measured under a light microscope. In addition, the clinic observed patients aged 18 to 60 years (n = 100), with hypertrophic scars in the face area that arose for various reasons. Of these, the 1st (control) group of patients (n = 10) received only one standard drug therapy, and the 2nd (main) group (n = 90) additionally received electrical stimulation with bipolar-pulsed microcurrents in the face area. Results. The experiment showed that the rate of resolution of the marker in the mesentery of the intestines of mice after a course of electrical stimulation was greater than in mice treated with the placebo procedure. In a clinical study in patients in the 2nd (main) group after a course of electrical stimulation, on the background of drug therapy, better results were achieved on the Vancouver Scar Scale and in a shorter time period than in patients in the 1st (control) group who received drug therapy . The greater effectiveness of the results in patients in the 2nd (main) group was confirmed by the data of statistical regression analysis. Conclusions. The results of this experiment showed that electrical stimulation by bipolar-pulsed microcurrents accelerates lymphatic drainage in the mesentery of the intestines of mice. In a clinical study, the use of electrical stimulation with bipolar-pulsed microcurrents in patients with hypertrophic scars in the face region in the 2nd group showed high efficiency and the transition of hypertrophic scars to normotrophic ones in earlier periods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.327
Threshold uncertainty score0.231

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.002
GPT teacher head0.270
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2019
Admission routes1
Has abstractyes

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