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Record W3162795275 · doi:10.15520/jcmro.v4i04.414

Interactions- Readdressing the issue

2021· article· en· W3162795275 on OpenAlexaff
Prolay Paul, L. M. Das, Tanushree BM, Berlin P Kurian, Sayantan Ghosh, Darshan JC, Arpan Roy, Sudip Dey

Bibliographic record

VenueJournal of Current Medical Research and Opinion · 2021
Typearticle
Languageen
FieldMedicine
TopicPharmaceutical Practices and Patient Outcomes
Canadian institutionsInstitute on Governance
Fundersnot available
KeywordsDrugAffect (linguistics)Drug interactionAccidentalMedicinePharmacologyPsychology

Abstract

fetched live from OpenAlex

Broadly drugs include all the chemical substances excluding food that affect the bodily processes. The drug is considered to be a medicine if it benefits the body. Whereas, if the drug is injurious to the body, it’s considered as a poison. Therefore, the same chemical can be a boon or curse with respect to the situation, condition of use, dosage and the individual using it. In this contemporary healthcare era, a huge number of medications are formulated each year and new interactions between drugs are reported every now and then. As a result, it is no more practical for doctors to be dependent on the memory alone to avoid possible drug interactions. Changes in absorption, distribution, metabolism or elimination of drugs are referred to as pharmacokinetic interactions, resulting in alteration in the level of drugs and its metabolites. The effect of drug changes from person to person than expected because it causes different reaction when a drug reacts with the food or dietary supplements they take (drug -food interaction). So, the effect of the drug is altered by means of increasing, decreasing, or producing a new effect which cannot be produced on its own the effect caused by food or dietary supplements. These interactions may occur due to accidental misuse or due to other factors such as lack of knowledge about it. This review provides a comprehensive literature review on various drug interaction. Generally, drug food interactions are neglected and not well defined but it can cause mild to serious effects. However, all clinicians, pharmacists and nurses should be aware of drug interaction to avoid the consequences caused by drug interactions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.008
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.900
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.523
GPT teacher head0.627
Teacher spread0.103 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2021
Admission routes1
Has abstractyes

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