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Record W3162801148 · doi:10.1093/nar/gkab346

The Dockstore: enhancing a community platform for sharing reproducible and accessible computational protocols

2021· article· en· W3162801148 on OpenAlexafffund
Denis Yuen, Louise Cabansay, Andrew Duncan, Gary Luu, Gregory Hogue, Charles Overbeck, Natalie Perez, Walt Shands, David Steinberg, C. Reid, Nneka Olunwa, Richard L. Hansen, Elizabeth A. Sheets, Ash O’Farrell, Kim Cullion, Brian D. O’Connor, Benedict Paten, Lincoln Stein

Bibliographic record

VenueNucleic Acids Research · 2021
Typearticle
Languageen
FieldDecision Sciences
TopicScientific Computing and Data Management
Canadian institutionsOntario Institute for Cancer Research
FundersNational Human Genome Research InstituteNational Heart, Lung, and Blood InstituteNational Cancer InstituteNational Institutes of HealthGovernment of CanadaU.S. Department of Veterans AffairsGenome CanadaOntario GenomicsOntario Genomics Institute
KeywordsWorkflowInteroperabilityComputer scienceVariety (cybernetics)World Wide WebCloud computingData scienceSoftwareSoftware engineeringDatabaseOperating system

Abstract

fetched live from OpenAlex

Dockstore (https://dockstore.org/) is an open source platform for publishing, sharing, and finding bioinformatics tools and workflows. The platform has facilitated large-scale biomedical research collaborations by using cloud technologies to increase the Findability, Accessibility, Interoperability and Reusability (FAIR) of computational resources, thereby promoting the reproducibility of complex bioinformatics analyses. Dockstore supports a variety of source repositories, analysis frameworks, and language technologies to provide a seamless publishing platform for authors to create a centralized catalogue of scientific software. The ready-to-use packaging of hundreds of tools and workflows, combined with the implementation of interoperability standards, enables users to launch analyses across multiple environments. Dockstore is widely used, more than twenty-five high-profile organizations share analysis collections through the platform in a variety of workflow languages, including the Broad Institute's GATK best practice and COVID-19 workflows (WDL), nf-core workflows (Nextflow), the Intergalactic Workflow Commission tools (Galaxy), and workflows from Seven Bridges (CWL) to highlight just a few. Here we describe the improvements made over the last four years, including the expansion of system integrations supporting authors, the addition of collaboration features and analysis platform integrations supporting users, and other enhancements that improve the overall scientific reproducibility of Dockstore content.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.024
metaresearch head score (Gemma)0.046
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Open science
Consensus categoriesnone
DomainCandidate signal: Reproducibility · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Software · Consensus signal: none
Teacher disagreement score0.988
Threshold uncertainty score0.127

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0240.046
Meta-epidemiology (narrow)0.0020.003
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0050.005
Science and technology studies0.0040.003
Scholarly communication0.0090.015
Open science0.0120.028
Research integrity0.0040.012
Insufficient payload (model declined to judge)0.0170.018

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.444
GPT teacher head0.530
Teacher spread0.087 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainReproducibility
GenreSoftware

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations38
Published2021
Admission routes2
Has abstractyes

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