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Record W3165547498 · doi:10.1139/apnm-2021-0007

Challenges in the design, interpretation, and reporting of randomized controlled clinical studies on the health effects of whole foods

2021· article· en· W3165547498 on OpenAlexaffvenueabout
Kathy Musa‐Veloso, Megan Racey, Amanda J MacFarlane, Dennis M. Bier, Benoı̂t Lamarche, Paula R. Trumbo, James D. House

Bibliographic record

VenueApplied Physiology Nutrition and Metabolism · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicNutrition, Genetics, and Disease
Canadian institutionsUniversity of ManitobaUniversité LavalHealth CanadaMcMaster UniversityIntertek (Canada)
Fundersnot available
KeywordsNoveltyBest practiceInterpretation (philosophy)Clinical trialMedicineAlternative medicineMedical educationPsychologyComputer sciencePolitical sciencePathology

Abstract

fetched live from OpenAlex

Given the challenges with nutrition research, the Canadian Nutrition Society and Intertek Health Sciences Inc held an expert consultation in late 2019 to discuss the development and implementation of best practices for clinical trials on whole foods. Key challenges in the design, interpretation, and reporting of clinical efficacy studies on whole foods and opportunities for the future development of best practices are reported. Novelty: Outlines existing tools, resources, and checklists for clinical nutrition trials and provides clear and tangible steps to develop best practices for studies on whole foods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.831
metaresearch head score (Gemma)0.911
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.169
Threshold uncertainty score0.208

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.8310.911
Meta-epidemiology (narrow)0.0030.004
Meta-epidemiology (broad)0.0080.006
Bibliometrics0.0090.010
Science and technology studies0.0040.020
Scholarly communication0.0180.009
Open science0.0120.010
Research integrity0.0080.020
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.057
GPT teacher head0.355
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
DomainReporting
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2021
Admission routes3
Has abstractyes

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