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Record W3165929547 · doi:10.21203/rs.3.rs-617877/v1

Factors Associated With Successful Publication for Systematic Review Protocol Registration: an Analysis of 397 Registered Protocols.

2021· preprint· en· W3165929547 on OpenAlexaff
Le Huu Nhat Minh, Huu‐Hoai Le, Gehad Mohamed Tawfik, Omar Mohamed Makram, Thuan Minh Tieu, Karim Mohamed Shahin, Ali Ahmed‐Fouad Abozaid, Jaffer Shah, Nguyen Hai Nam, Nguyen Tien Huy

Bibliographic record

VenueResearch Square · 2021
Typepreprint
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsMcGill University
Fundersnot available
KeywordsProtocol (science)Trial registrationSystematic reviewMedicineComputer scienceMedical physicsMEDLINEClinical trialAlternative medicinePolitical scienceInternal medicinePathologyLaw

Abstract

fetched live from OpenAlex

Abstract Background: Meta-analyses are on top of the evidence-based medicine pyramid, yet many of them are not completed after they are begun. Many factors impacting the publication of meta-analysis works have been discussed, and their association with publication likelihood has been investigated. These factors include the type of systematic review, journal metrics, h-index of the corresponding author, country of the corresponding author, funding sources, and duration of publication. In our current review, we aim to investigate these various factors and their impact on the likelihood of publication. A comprehensive review of 397 registered protocols retrieved from five databases was performed to investigate the different factors that might affect the likelihood of publication. These factors include the type of systematic review, journal metrics, h-index of the corresponding author, country of the corresponding author, funding sources, and duration of publication.Results: We found that corresponding authors in developed countries and English-speaking countries had higher likelihoods of publication: 206/320 (p=0.018) and 158/236 (p=0.006), respectively. Our models of multivariable logistic regression analysis revealed that two main factors impact the publication outcome: updated protocol status of the published review paper (OR: 1.7, 95% CI: 1.0-2.8, p=0.037) and external funding (OR: 2.1, 95% CI: 1.2-3.8, p=0.01). However, corresponding authors’ location in developed countries (OR: 1.7, 95% CI: 0.8-3.4, p=0.139) and English-speaking countries (OR: 1.5, 95% CI: 0.9-2.6, p=0.1) were insignificant determinants.Conclusion: Meta-analyses continue to be on top of the evidence hierarchy, rendering them the key to informed clinical decision-making. Therefore, more attention should be paid to the methodological quality of this type of publication.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.411
metaresearch head score (Gemma)0.787
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.589
Threshold uncertainty score0.727

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.4110.787
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0070.012
Bibliometrics0.0160.036
Science and technology studies0.0020.003
Scholarly communication0.0080.011
Open science0.0040.007
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.0150.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.859
GPT teacher head0.651
Teacher spread0.209 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designObservational
DomainReporting
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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