Consumption of buckwheat modulates the post‐prandial response of selected gastrointestinal satiety hormones: a randomized, clinical trial with Fagopyrum esculentum moenech (common buckwheat)
Bibliographic record
Abstract
Buckwheat (BW) consumption has been linked to improved glycemic control; however, evidence from randomized, placebo‐controlled trials is lacking. Our objective was to assess the post‐prandial response of glucose, insulin and gastrointestinal hormones affecting glycemia and satiety after consumption of BW. Twelve control participants and 12 with type 2 diabetes were recruited and asked to consume crackers containing 50 grams of available carbohydrate made from BW or rice flour, in random order, on two separate occasions. Blood samples were taken 0, 15, 30, 45, 60, 120 and 180 minutes after consumption. Plasma responses of glucose, insulin, C‐peptide, incretin and satiety hormones were assessed using total area under the curve (tAUC). Glucose, insulin and C‐peptide were not affected by BW consumption. There was a trend for tAUC of the incretin hormone glucagon‐like peptide 1 to be higher after BW consumption while paradoxically the tAUC for glucose‐dependent insulinotropic peptide, another incretin hormone, was lower. Although tAUC of ghrelin and peptide YY were not different between rice and BW, there was a trend for tAUC of the anorexigenic hormone pancreatic polypeptide to be higher after consumption of BW. Overall, a food product made from BW containing 50 grams of available carbohydrate does not modify post‐prandial glycemia or insulinemia; however, changes in satiety hormones warrants further study. Grant Funding Source : Manitoba Functional Foods Opportunity Program; Agri‐food Research & Development Initiative; Manitoba Agri‐health Research Network
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.006 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".