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Record W3174150961 · doi:10.1016/j.cell.2021.06.004

Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy

2021· article· en· W3174150961 on OpenAlexaff
Vivien Béziat, Franck Rapaport, Jiafen Hu, Matthias Titeux, Mathilde Bonnet des Claustres, Mathieu Bourgey, Heather Griffin, Élise Bandet, S. Cindy, Roya Sherkat, Hassan Rokni‐Zadeh, David M. Louis, Majid Changi‐Ashtiani, Ottavia M. Delmonte, Toshiaki Fukushima, Tanwir Habib, Andrea Guennoun, Taushif Khan, Noemi Bender, Mahbuba Rahman, Frédégonde About, Rui Yang, Geetha Rao, Claire Rouzaud, Jingwei Li, Debra A. Shearer, Karla K. Balogh, Fatima Al Ali, Manar Ata, Soroosh Dabiri, Mana Momenilandi, Justine Nammour, Marie‐Alexandra Alyanakian, Marianne Leruez‐Ville, David Guenat, Marie Materna, Léa Marcot, Natasha Vladikine, Christine Soret, Hassan Vahidnezhad, Leila Youssefian, Amir Hossein Saeidian, Jouni Uitto, Émilie Catherinot, Shadi Sadat Navabi, Mohammed Zarhrate, David T. Woodley, Mohamed Jeljeli, Thomas Abraham, Serkan Belkaya, Lazaro Lorenzo, Jérémie Rosain, Mousa Bayat, Fanny Lanternier, Olivier Lortholary, Faramarz Zakavi, Philippe Gros, Gérard Orth, Laurent Abel, Jean‐Luc Prétet, Sylvie Fraitag, Emmanuelle Jouanguy, Mark M. Davis, Stuart G. Tangye, Luigi D. Notarangelo, Nico Marr, Tim Waterboer, David Langlais, John Doorbar, Alain Hovnanian, Neil D. Christensen, Xavier Bossuyt, Mohammad Shahrooei, Jean‐Laurent Casanova

Bibliographic record

VenueCell · 2021
Typearticle
Languageen
FieldImmunology and Microbiology
TopicImmunodeficiency and Autoimmune Disorders
Canadian institutionsMcGill University Health CentreMcGill University
FundersNational Center for Advancing Translational SciencesNational Institute of Allergy and Infectious DiseasesMedical Research CouncilAgence Nationale de la RechercheCancer Research UK
KeywordsBiologyGeneticsVirologyImmunology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.025

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.225
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations92
Published2021
Admission routes1
Has abstractno

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