EFFECT OF HYPERBARIC OXYGEN ON THE RAT CARDIOMYOCYTE AFTER 6 HOURS OF AN ACUTE MYOCARDIAL INFARCTION
Bibliographic record
Abstract
The current treatment of myocardial infarct (MI) is thrombolysis, or ideally percutaneous coronary angioplasty. Alternatively, benefits of hyperbaric oxygen (HBO) have been reported during an MI in progress, where it seems to reduce the number of infarcted cardiomyocytes favoring their neovascularization. Material and methods MI was induced by ligation of the anterior descending coronary artery. HBO was administered by a hyperbaric chamber 100%, at 2 atmospheres of pressure, for one hour daily for 15 days. After this time the rats were sacrificed, the size of the infarcted area was measured histologically, and the number of vascular buttons and neoformation vessels was determined by detecting the Vascular Endothelial Growth Factor (VGEFR2) and CD34 by immunohistochemistry, respectively. Three groups of 10 rats each were compared: group A (HBO without MI), group B (MI with HBO), and group C (MI without HBO). Results Immunohistochemically, a greater number of VEGFR2 positive vascular buttons were found in the rats of group C than those of group B (7.15 vs 2.55 per field, p = 0.01), but in the group B there are more CD34 positive neoformation vessels (7.8 vs 4.2 per field, p = 0.01). Conclusions HBO promotes early neovascularization of the rat cardiomyocyte after 6 hours of an MI. Support or Funding Information SIP, COFAA, IPN This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".