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Record W3180554220 · doi:10.5267/j.ccl.2021.6.001

Preparation and biological activity evaluation of some benzoylthiourea and benzoylurea compounds

2021· article· en· W3180554220 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueCurrent Chemistry Letters · 2021
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicInsect Pest Control Strategies
Canadian institutionsnot available
Fundersnot available
KeywordsChemistryInsect growth regulatorInstarPhenylhydrazineLarvaMoultingDiflubenzuronChitinCuticle (hair)CarboxamideToxicologyPharmacologyStereochemistryBiochemistryOrganic chemistryChitosanBotanyBiologyAnatomy

Abstract

fetched live from OpenAlex

Due to the complicated problems coming from excessive applications of insecticides, searching for safe substitutes to these insecticides has become a necessity. Thus, the insect growth regulators are candidates to be used in such concern. Comparative studies of the effects of three compounds, 2-benzoyl-N-phenylhydrazine-1-carbothioamide (1), 2-(cyanoacetyl)-N-phenylhydrazine-1-carboxamide (2) and N-(2-(2-cyanoacetyl)hydrazinecarbonothioyl)furan-2-carboxamide (3) (an insect growth regulator inhibiting chitin synthesis), were conducted on Spodoptera littoralis (Boisduval, 1833). The compounds, orally administered, caused larval mortality proportional to the concentrations in the food source. larvae were unable to complete the molting process and died in the old larval cuticle. Larvae contaminated by sublethal doses completed their development to adulthood. N-(2-(2-cyanoacetyl)hydrazinecarbonothioyl)furan-2-carboxamide (3) is more active than the other compounds have LC50 17.082 ppm for 2nd instar larvae and 60.832 ppm for 4th instar larvae.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.413
Threshold uncertainty score0.201

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.290
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it