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Record W3186411542 · doi:10.1002/jrsm.1515

Measurement error in <scp>meta‐analysis</scp> (<scp>MEMA</scp>)—A Bayesian framework for continuous outcome data subject to non‐differential measurement error

2021· review· en· W3186411542 on OpenAlexaff
Harlan Campbell, Valentijn M. T. de Jong, Lauren Maxwell, Thomas Jaenisch, Thomas P. A. Debray, Paul Gustafson

Bibliographic record

VenueResearch Synthesis Methods · 2021
Typereview
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsCovariateBayesian probabilityObservational errorOutcome (game theory)Computer scienceStatisticsRegression analysisMeta-analysisMeta-regressionPoint estimationRegressionLinear regressionErrors-in-variables modelsEconometricsMathematicsMachine learningArtificial intelligenceMedicine

Abstract

fetched live from OpenAlex

Ideally, a meta-analysis will summarize data from several unbiased studies. Here we look into the less than ideal situation in which contributing studies may be compromised by non-differential measurement error in the exposure variable. Specifically, we consider a meta-analysis for the association between a continuous outcome variable and one or more continuous exposure variables, where the associations may be quantified as regression coefficients of a linear regression model. A flexible Bayesian framework is developed which allows one to obtain appropriate point and interval estimates with varying degrees of prior knowledge about the magnitude of the measurement error. We also demonstrate how, if individual-participant data (IPD) are available, the Bayesian meta-analysis model can adjust for multiple participant-level covariates, these being measured with or without measurement error.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.323
metaresearch head score (Gemma)0.596
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.677
Threshold uncertainty score0.835

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.3230.596
Meta-epidemiology (narrow)0.0030.004
Meta-epidemiology (broad)0.0090.015
Bibliometrics0.0080.011
Science and technology studies0.0010.004
Scholarly communication0.0090.005
Open science0.0070.007
Research integrity0.0070.009
Insufficient payload (model declined to judge)0.0080.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.949
GPT teacher head0.682
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designTheoretical or conceptual
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2021
Admission routes1
Has abstractyes

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